Disorder - Epidermolysis bullosa, junctionalis

Organ Systems Involved
Integument

Alternative disorders described within LIDA

Dystrophic epidermolysis bullosa; Epidermolysis bullosa simplex (epidermolytic epidermolysis bullosa)

Alternative Names
Junctional epidermolysis bullosa; Congenital epidermolysis bullosa; Epidermolysis bullosa congenita; Mechanobullous skin disease; Dermolytic epidemolysis bullosa

Presenting Signs

This condition is commonly seen as blistered skin. There are reports of nails separating completely from the nail beds, along with malformation of the nails. Nail beds commonly become infected as a secondary consequence of the nail loss. Ulcers of the skin over areas where the skin is in close contact with bones is reported, as is ulceration of the gums, tongue and foot pads. Affected cats may also have eye ulcers.

Cats at Risk

Newborns, juvenile cats

Breeds Affected
Siamese


Treatment

No specific treatment recognised. Treatment of symptoms as they arise with the aim of improving quality of life is all that is available. An attempt can be made to reduce the possibility of trauma to affected cats and treatment of secondary infections can be undertaken where necessary. Problems are much less severe in this disease than in the similar disease, dystrophic epidermolysis bullosa. Regardless of this, euthanasia is also a common outcome of this disease.

PubMed References
Epidermolysis bullosa, junctionalis

Contributor
Tamara Butler