Disorder - Amyloidosis lambda

Organ Systems Involved
Systemic

Alternative disorders described within LIDA

Amyloidosis, Amyloidosis, AA, Amyloidosis, renal

Alternative Names
Glomerulonephropathy

Presenting Signs

Amyloidosis lambda is a disease process where a particular type of protein, known as amyloid lambda, is deposited in various organs around the body. This protein is often produced when certain types of tumours are present, such as multiple myeloma. Alternatively, amyloid production in the body may occur for unknown reasons. Deposits of amyloid are commonly found in organs such as the kidneys, heart, liver, lungs, gastrointestinal tract and skin. The accumulation of amyloid in these areas causes inflammation and cell damage. Symptoms will depend on the organ affected and the amount of protein deposited. Often dullness, lack of appetite, vomiting, a painful enlarged abdomen or diarrhoea are seen, as well as raised, waxy lumps on the skin.

Treatment

Medical. Treating amyloidosis involves reducing the inflammatory response that is caused by the protein damaging organs. In general, amyloidosis is very difficult to treat.

PubMed References
Amyloidosis lambda

Contributor
Audrey Hoh