Disorder - Hypomyelination of the central nervous system

Organ Systems Involved
Nervous/sensory

Alternative Names
Congenital tremors

Presenting Signs

This is an inherited disease involving the abnormal development of nerves. The nerves are normally sheathed in a substance called myelin, and in this condition the myelin sheath is deficient. Animals affected by this disease show clinical signs at birth or start showing clinical signs within a few days after birth. Symptoms include walking abnormalities, generalised tremors and involuntary eye tremors.

Breeds Affected
Siamese


PubMed References
Hypomyelination of the central nervous system

Contributor
Satoshi Yoneyama