Disorder - Ovarian dysgenesis

Organ Systems Involved
Urogenital

Alternative disorders described within LIDA
    Gonadal dysgenesis

Presenting Signs
    Ovarian dysgenesis is a problem in the development of the ovaries in female animals. Changes in the chromosomes (DNA strands involved in inheritance) cause the errors in the development of the sex glands. Normal male animals carry an X-Y pair of sex chromosomes, while normal female animals carry an X-X pair of sex chromosomes. These chromosomes determine whether an animal develops into a male or a female. In ovarian dysgenesis, the female animals affected only have one X chromosome instead of the normal pair (X-X). This cause a failure in the development of one or both ovaries.

    If the animal affected has dysgenesis of both ovaries, they are sterile (unable to become pregnant). However, if only one ovary is affected, the animal may appear completely normal and is able to reproduce.

Cats at Risk
    Ovarian dysgenesis is a problem in the development of the ovaries in female animals. Changes in the chromosomes (DNA strands involved in inheritance) cause the errors in the development of the sex glands. Normal male animals carry an X-Y pair of sex chromosomes, while normal female animals carry an X-X pair of sex chromosomes. These chromosomes determine whether an animal develops into a male or a female. In ovarian dysgenesis, the female animals affected only have one X chromosome instead of the normal pair (X-X). This cause a failure in the development of one or both ovaries.

    If the animal affected has dysgenesis of both ovaries, they are sterile (unable to become pregnant). However, if only one ovary is affected, the animal may appear completely normal and is able to reproduce.

Treatment
    There is no treatment for ovarian dysgenesis.

PubMed References
Ovarian dysgenesis

Contributor
Ray Chan