Disorder - Factor VII Deficiency in Dog

Organ Systems Involved
Cardiovascular

Alternative Names
Hypoproconvertinaemia
Hypoproconvertinemia

Brief Description

A condition where the dog has a deficiency of Factor VII, a protein in the blood that, when activated in healthy dogs, accelerates the process of blood clotting.

Presenting Signs

This disorder is usually discovered by chance as it has no obvious clinical signs or symptoms. However, in some dogs there may be a tendency to have mild bleeding and to bruise easily or excessively. The glands in the neck may also become inflamed and swollen and there may be an accumulation of blood-tinged fluid in the head and neck regions. Often this condition has no serious implications and treatment is usually unnecessary. However although it has never yet been reported, there is speculation that if Factor VII drops to very low levels, the dog may be unable to stop any incident of excessive bleeding, and this may lead to death.

Groups Affected
Hound
Utility


Breeds Affected
Alaskan malamute
Basset hound
Beagle


PubMed References
Factor VII Deficiency in Dog

Further Reference Material [OMIA Number]
361


Contributor
Dorothy Cheong