Disorder - Autoimmune thrombocytopoeniaOrgan Systems Involved
Immune mediated thrombocytopoenia
Platelet Function Defect
A condition where the animal has excessive bleeding due to a deficiency of the cells known as thrombocytes or platelets, which are responsible for the clotting of blood.
Autoimmune thrombocytopoenia is a condition in which the immune system mistakenly recognises its own normal platelets as foreign. Because of this, the body attacks the platelets and destroys them. As these cells are necessary for the formation of blood clots, the deficiency causes a delay in blood clotting and the animal bleeds for much longer than usual. In severe cases, massive bleeding can occur either from wounds or internally. The resulting blood loss causes the animal to be lethargic, weak and to have a reduced appetite. As the blood is responsible for the transport of oxygen around the body the dog will try to compensate by increasing the heart rate and panting, in an attempt to carry more oxygen around the body. In severe cases the blood loss may be so extreme that it causes death.
Dogs at Risk
Females are three to four times more prone to this condition than males.
American cocker spaniel
Australian silky terrier
Cavalier King Charles spaniel
Dachshund (long, smooth and wire haired)
Dachshund (miniature - long, smooth and wire-haired)
Kerry blue terrier
Old English sheepdog
Pyrenean mountain dog
Swiss mountain dog
Autoimmune Hemolytic Anaemia Haemophilia Von Willebrand's disease
Further Reference Material [OMIA Number]