Disorder - Tremor syndrome with central axonopathy

Organ Systems Involved
Nervous/sensory

Alternative Names
Acquired tremor in young adult dogs

Brief Description

A disorder of the brain and spinal cord in which nerves are missing their normal fatty covering and become spontaneously 'excited', causing tremors of the entire body.

Presenting Signs

This disorder usually develops suddenly in young adult dogs (six months to three years of age). The signs become progressively worse over one to three days and then remain the same until is begun. There is an all-over tremor that can range from mild to so severe that the dog may have difficulty walking. This is called an intention tremor, meaning that it is worse when the animal is excited or tries to perform a specific action (such as eating or walking towards an object). The tremor decreases or disappears when the dog is relaxed or at rest. There are commonly rapid, random eye movements as well.

Dogs at Risk

Tremor syndrome with central axonopathy mostly affects white dogs.

Treatment

Medical

Related Disorders

Chorea
Pelizaeus-Merzbacher disease
Myoclonia
Shaking pup
White dog shaker syndrome
Cerebrospinal hypomyelinogenesis

PubMed References
Tremor syndrome with central axonopathy

Further Reference Material [OMIA Number]
770


Contributor
Kelly Davis