Feline Alimentary Lymphoma (LGAL) and Lymphoplasmacytic Enteritis (LPE)


Beata Ujvari

Gastrointestinal lymphomas are probably the most common haemopoietic neoplasm in domestic cats. Environmental conditions and diet are amongst the possible risk factors that have been considered for causing the disease.
Despite the common prevalence appropriate diagnosis and treatment can be difficult due to other conditions sharing analogous clinical signs. For example feline low grade alimentary lymphoma (LGAL) and lymphoplasmacytic enteritis (LPE) have similar clinical presentations. The Small Animal Clinical Research Team is currently working on developing accurate and correct diagnostic techniques to guide appropriate treatment and prognostic information.

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LGAL

LGAL showing expression of MHC class II by enterocytes. IHC.

LPE

LPE showing expression of MHC class II by enterocytes. IHC.


From: Briscoe et al. 2011. Journal of Comparative Pathology, 145: 187-198.