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Haferkamp S, Scurr LL, Becker TM, Frausto M, Kefford RF, Rizos H. Oncogene-induced senescence does not require the p16(INK4a) or p14ARF melanoma tumor suppressors. J Invest Dermatol. 2009 Aug;129(8):1983-91.- view abstract |
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McKenzie H, Becker TM, Scurr LL, Kefford RF, Rizos H. Wild type and melanoma-associated mutant p16(IN4a) proteins do not oligomerize in vivo. Pigment Cell Melanoma Res. 2009 Feb;22(1):131-3. |
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Becker TM, Haferkamp S, Dijkstra MK, Scurr LL, Frausto M, Diefenbach E, Scolyer RA, Reisman DN, Mann GJ, Kefford RF, Rizos H. The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. Mol Cancer. 2009 Jan 16;8:4. - view abstract |
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Scurr LL, Guminski AD, Chiew YE, Balleine RL, Sharma R, Lei Y, Pryor K, Wain GV, Brand A, Byth K, Kennedy C, Rizos H, Harnett PR, deFazio A. Ankyrin repeat domain 1, ANKRD1, a novel determinant of cisplatin sensitivity expressed in ovarian cancer. Clin Cancer Res. 2008 Nov 1;14(21):6924-32. - view abstract |
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Gallagher SJ, Thompson JF, Indsto J, Scurr LL, Lett M, Gao BF, Dunleavey R, Mann GJ, Kefford RF, Rizos H. p16INK4a expression and absence of activated B-RAF are independent predictors of chemosensitivity in melanoma tumors. Neoplasia. 2008 Nov;10(11):1231-9. - view abstract |
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Haferkamp S, Becker TM, Scurr LL, Kefford RF, Rizos H. p16INK4a-induced senescence is disabled by melanoma-associated mutations. Aging Cell. 2008 Oct;7(5):733-45. - view abstract |
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Rizos H, Scurr LL, Irvine M, Alling NJ, Kefford RF. p14ARF regulates E2F-1 ubiquitination and degradation via a p53-dependent mechanism. Cell Cycle. 2007 Jul 15;6(14):1741-7 - view abstract |
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Packer LM, Pavey SJ, Boyle GM, Stark MS, Ayub AL, Rizos H, Hayward NK. Gene expression profiling in melanoma identifies novel downstream effectors of p14ARF. Int J Cancer. 2007 Aug 15;121(4):784-90. - view abstract |
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Rizos H, McKenzie HA, Ayub AL, Woodruff S, Becker TM, Scurr LL, Stahl J, Kefford RF. Physical and functional interaction of the p14ARF tumor suppressor with ribosomes. J Biol Chem. 2006 Dec 8;281(49):38080-8. - view abstract |
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Gallagher SJ, Kefford RF, Rizos H.The ARF tumour suppressor. Int J Biochem Cell Biol. 2006 Feb 28. - view abstract |
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Becker TM, Rizos H, de la Pena A, Leclercq
IA, Woodruff S, Kefford RF, Mann GJ. Impaired inhibition of
NF-kappaB activity by melanoma-associated p16 INK4a mutations. Biochem
Biophys Res Commun. 2005 Jul 8;332:873-9. - view
abstract |
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Becker TM, Ayub AL, Kefford RF, Mann GJ,
Rizos H. The melanoma-associated 24 base pair duplication in
p16 INK4a is functionally impaired. Int J Cancer.
2005 Jun 8; - view
abstract |
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Rizos H, Woodruff S, Kefford
RF. p14ARF interacts with the SUMO-conjugating enzyme Ubc9
and promotes the sumoylation of its binding partners. Cell
Cycle 2005 Apr;4:597-603. - view
abstract |
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Gallagher, S., Kefford, R., Rizos, H.
2004. Enforced expression of p14ARF induces p53-dependent cell
cycle arrest but not apoptosis. Cell Cycle. 2005 Mar;4:465-72.- view
abstract |
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Rizos, H., Diefenbach, E., Badhwar, P.,
Woodruff, S., Becker, T. M., Rooney, R. J. and Kefford, R.F.
2003. Association of p14ARF with the p120E4F transcriptional
repressor enhances cell cycle inhibition. J. Biol. Chem
278, 4981-4989. - view
abstract |
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Rizos, H., Darmanian, A., Holland, E.A.,
Mann, G.J and Kefford, RF. 2001. Mutations in the INK4a/ARF locus
functionally impair p14ARF. J Biol Chem 276, 41424-41434.
- view
abstract |
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Rizos, H., Puig, S., Badenas, C., Malvehy,
J., Darmanian, A. P., Mila, M. and Kefford, RF. 2001. A melanoma-associated
germline mutation in exon 1ß inactivates p14ARF. Oncogene 20,
5543-5547. - view
abstract |
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Becker, T. M., Rizos, H., Kefford, R.F.
and Mann, G.J. 2001. Functional impairment of melanoma-associated
p16 INK4a mutants in melanoma cells despite retention
of cyclin-dependent kinase 4 binding. Clin Cancer Res 7,
3282-3288. - view
abstract |
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Rizos, H., Darmanian, A., Mann, G.J and
Kefford, RF. 2000. Two arginine rich domains in the p14ARF
tumour suppressor mediate nucleolar localisation. Oncogene 19,
2978-2985. - view
abstract |
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Rizos, H., Becker, T. M., Holland, E.
A., Kefford, R. F. and Mann, G. J. 1997. Differential expression
of p16 INK4a and p16ß transcripts in hereditary
melanoma families without CDKN2A exon mutation. Oncogene 15,
515-523. - view
abstract |
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Rizos, H., Darmanian, A., Indsto, J. O.,
Shannon, J., Kefford, RF. and Mann, G.J. 1997. Multiple abnormalities
of the pRb regulatory pathway in cultured melanoma cells. Melanoma
Research 9, 1-10. - view
abstract |
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Holland, E. A., Beaton, S. C., Becker,
T. M., Grulet, O. M. C., Peters, B. A., Rizos, H., Kefford,
R. F. and Mann, G. J. 1995. Analysis of the p16 gene, CDKN2,
in 17 Australian melanoma kindreds. Oncogene 11, 2289-2294.
- view
abstract |
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