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Theory and method in biosciences

Applying the philosophy of science to bioscience research

We advance science by removing conceptual and methodological roadblocks. Through high-level biological theory, we promote an integrative approach to research in non-communicable diseases.

We encourage an integrative approach to non-communicable diseases by harnessing the potential of biological theory and evolutionary medicine.

Our research in non-communicable diseases aims to:

  • utilise methodological analysis,
  • develop conceptual and modelling tools
  • use microbes in modelling and analysing the causal foundations of biological information.

Combining expertise in the philosophy of science with the knowledge of bioscience, we obtain scientific value from theoretical work on key aspects of the scientific process.

Our largest project conducts foundational research on how to measure and integrate the genetic, epigenetic and exogenetic causes of phenotypes – the observable characteristics of an individual resulting from the interaction of its genotype with the environment.

  • Professor Paul Griffiths, Arts and Social Sciences, University of Sydney [Project lead]
  • Dr John Matthewson, Massey University
  • Dr Arnaud Pocheville – Arts and Social Sciences, University of Sydney
  • Professor Peter Godfrey Smith, Science, University of Sydney
  • Associate Professor Andrew Holmes, Science, University of Sydney
  • Professor David Raubenheimer, Veterinary Science, University of Sydney
  • Dr Pierrick Bourrat, Arts and Social Sciences, University of Sydney
  • Dr Karola Stotz, Macquarie University
  • Professor Paul Rainey, Massey University
  • Dr Brett Calcott, Arts and Social Sciences, University of Sydney

Visit the Griffiths Lab site for more information our research projects, publications and events.


  • Biology
  • Populations
  • Society and environment
  • Solutions




Project lead

Professor Paul Griffiths
Professor Paul Griffiths
"My collaboration with CPC Nepean about the evolution of pregnancy would never have happened without the Charles Perkins Centre."
Visit Paul Griffiths' profile