This unit of study begins with a description and analysis of the basic anatomical organization of the musculoskeletal and nervous (central and peripheral) systems. The structure and function of excitable cells, muscle and nerve, will lead to a discussion of membrane potential, synaptic transmission and neuromuscular junction. After consideration of the mechanisms of contraction, the way in which nerve signals are integrated and coordinated are covered in more detail. The receptors involved in normal modes of communications are discussed, This is complemented by an introduction to nervous system pharmacology, focusing on the autonomic nervous system and central nervous system, with special reference to pain and analgesia. An appreciation is gained of how toxins and infections can disturb normal neuromuscular coordination and nervous system function. Thus, pharmacological and pathological considerations are studied with relevance to the anatomical, histological and physiological concepts. Special senses such as vision and hearing are also introduced. In practical classes, students perform experiments to illustrate the functioning of motor control, coordination and the senses. In addition, students extend their anatomical and histological expertise by examining prosections and prepared microscope slides. Practical classes also include the effects of analgesics on experimental pain and case studies of tetanus and botulism. Sessions are also designed to nurture experimental design, hypothesis testing and data analysis skills.
2 lectures and 2-4 hrs prac/tut per week.
One 2hr theory exam (60%), two in-semester assessments (40%).
Human Physiology: An integrated approach Silverthorn D Pearson/Benjamin Cummings, 6th Edition, 2013; The Anatomy Coloring Book Kapit W and Elson LM Benjamin Cummings, 4th Edition, 2015; Gray's Anatomy for Students Drake RL, Vogl W and Mitchell AWM Elsevier, 3rd Edition 2014; Prescott's Microbiology Willey JM, Sherwood LM and Woolverton CJ McGraw-Hill, 9th Edition, 2014; Histology: A text and Atlas Ross MH and Pawlina W Lippincott, Williams and Wilkins, 7th Edition, 2015; Medical Pharmacology at a Glance Neal MJ Blackwell Science, 7th Edition, 2012; Rang and Dale's Pharmacology Rang HP, Dale MM, Ritter JM, Flower RJ and Henderson G Churchill Livingstone, 8th Edition, 2015; Robbins Basic Pathology Kumar V, Abbass AK and Aster J Elseview/Saunders, Philadelphia, 9th Edition, 2013.
30 credit points from [12cp from CHEM1XXX and 12cp from MATH1XXX and 12cp from (BIOL1XXX, MBLG1XXX)]Prohibitions
ANAT2008 or ANAT2010 or ANAT2011 ANAT2910 or BCHM2072 or BCHM2972 or BIOL2006 or BIOL2016 or BIOL2906 or BIOL2916 or BMED2806 or IMMU2101 or MICR2021 or MICR2022 or MICR2921 or MICR2922 or NUTR2911 or NUTR2912 or PCOL2011 or PHSI2005 or PHSI2006 or PHSI2905 or PHSI2906