The course will have two concurrent themes. Clinical Immunology: this theme will concentrate on the immunological methods used to evaluate human disease and will include the theoretical basis for tests of immune function, practical laboratory application of assays based on these principles and case-based seminars. The application of these methods to translational immunology will be discussed in a range of immune-mediated diseases. Research: This theme will focus on understanding the investigation of immune function with lectures and practical sessions reviewing current molecular and cellular approaches and seminars based on study of current literature and classic papers in Immunology. Instruction will comprise lectures on the immunopathology of disease, the immunological methods used in diagnosis and research and translation into new immunological interventions; laboratory classes on methods and techniques used in clinical diagnosis and research investigations; and tutorials involving clinical cases, journal article reviews, review of laboratory problems and seminars consisting of presentation of specified topics researched by individual students. The learning objectives of this unit are: 1. to understand the immunological basis for infection and immunity and how these concepts are core to and applied in the diagnostic pathology laboratory; 2. to understand how the immune system causes and prevents disease, the use and performance of immunological tests in the investigation of disease and methods of investigation of the immune system; 3. to develop effective skills in problem-solving and self-directed learning; and 4. to foster advanced verbal and written communication skills.
2x1hr lecture/week; 1x2hr practical classes or tutorials or seminars/week
1x2hr formal written examination (50%), progressive assessments including tutorial assignment, seminar presentation, and one formative assessment (50%).
Clinical Immunology and Serology: A Laboratory Perspective, 3nd Edition Stevens CD. F. A. Davis Company, Philadelphia, 2010.This is a reference book that should not be purchased, and a copy will be available in practical classes and the library.
It is preferable to complete INIM5001, Fundamental Immunology, in First Semester, before Clinical and Translational Immunology. But this is not essential if a student starting in Second Semester has previously studied undergraduate immunology.
Undergraduate immunology; undergraduate bacteriology and virology