This unit will explore the physicochemical properties of drugs and how this determines the interactions of small molecules (drugs) with biological macromolecules (enzymes and receptors). All stages in the process of drug design and development will be investigated, including computational drug design, structure activity studies, synthesis and activity assays. Students will also gain experience in a variety of experimental techniques related to drug design. In addition, students will develop skills including critical thinking, the use of information technology and report writing.
2 x lectures/wk, 5 x 2hr tutorials, 4 x 4hr workshops and self-directed learning
Exam (60%), laboratories (20%), and molecular modeling (20%)
Patrick GL. An Introduction to Medicinal Chemistry (5th ed). Oxford University Press, 2013
3 credit points of Calculus, 3 credit points of Statistics, 6 credit points of Biochemistry, 12 credit points of Chemistry. Students who have not completed up to 12 credit points of pre-requisite subjects are strongly advised to take the corresponding Bridging Course offered in February, July and as a distance course at other times of the year.