The determinants of maximal active muscle force and power production are examined in terms of the crossbridge cycle, sarcomere arrangement, myosin isoforms and the extent of muscle activation. Evidence for neural adaptations to high resistance training is examined and the practical significance of these adaptations is discussed. The responses of skeletal muscle to high-resistance training are discussed in terms of i) the control of protein synthesis, ii) sarcomere remodelling and myofibril assembly, and iii) whole muscle hypertrophy and fibre type shifts. An evidence-based approach is used to examine the dose-response relationship between high-resistance variables (load, number of sets, training, frequency, rest interval) and hypertrophy. Muscle structural and functional adaptations to disuse (bed rest, non-weight bearing, immobilization) are examined, as well as the effects of re-ambulation and re-training.
2hr lecture/week, 2hr practical/week
Mid semester exam (30%), practical exam (10%), end semester exam (60%)
No textbook required, students are recommended to obtain unit of study manual
Background in basic human biology (e.g. high school level) including knowledge of biologically important molecules and the basic structure and function of the cell.