This unit of study aims to build on the student's basic knowledge of microbiology by providing an awareness of modern concepts and the latest knowledge of medical bacteriology at the molecular level. This knowledge is relevant to the susceptibility and response of the host to pathogenic bacteria. There is a particular emphasis on the host-pathogen relationship at the cellular and molecular levels regarding symptoms, virulence factors, pathogenesis, diagnosis, treatment, control and prevention. The practical component will allow candidates to become familiar with modern molecular-based bacteriological techniques used to identify the characteristic genetic features of bacterial species that cause infections. The unit will provide an advanced scientific and intellectual base to augment student's knowledge and understanding, at a postgraduate level, in a career involving medical microbiology or in a related subject area. Lectures will be used to impart knowledge and understanding as well as review key themes of the module, and many of these will be given by experts in the current field. Tutorials will utilise activities such as journal review and topic presentation which enable develop their skills by presenting research on a range of issues including advances in knowledge on bacterial pathogenesis, identification and treatment in Australia and worldwide. The use of case studies will enable candidates to examine breakouts of disease and their investigation by the clinical laboratory. Laboratory sessions will enable students to apply the theoretical concepts of laboratory investigation at the molecular level using advanced molecular techniques of DNA, RNA and protein purification and analysis.
2x1hr lectures/week; 2x2hr practical classes or tutorials or student presentations/week
1x2hr closed-book (Theory) exam, and 1x1.5hr closed book (Theory of Practical) exam Value: Theory exam (50%) Progressive assessment (50%) including class tutorial/presentations (25%), practical exam (15%) and laboratory book assessment (10%).
While all material for examination is contained within the lectures, tutorials and practical classes, students who wish to learn more can undertake further reading. Recommended texts for further reading: Bacterial Pathogenesis: A Molecular Approach, Third Edition; Brenda A. Wilson, Abigail A. Salvers, Dixie D. Whitt, and Malcolm E. Winkler ASM Press 2011. Bacterial Pathogens and Their Virulence Factors, Douglas I. Johnson, Springer International Publishing 2018.Although these are recommended, other texts are equally sound. We suggest you discuss with the unit coordinator, Jim Manos, before making a textbook purchase.
Undergraduate Microbiology or Infectious Diseases