Inflammation and immunopathology are encountered frequently in surgical practice, in settings such as acute pancreatitis, inflammatory bowel disease and rejection of organ transplants. Manipulation of the immune system through treatment with checkpoint inhibitors and other forms of immunotherapy is assuming increasing importance in the treatment of malignant melanoma and various other cancers. This unit of study will introduce students to the fundamental aspects of innate and cognate immune responses and their relationship to the clinical manifestations of some common surgical conditions.
The unit is delivered online and will require approximately 10 hours study per week.
Formative multiple choice question assessment of pre-existing knowledge in Immunobiology allows students to identify strengths and weaknesses before starting the leaning modules. Short-answer questions cover the knowledge acquired in each module. Students may access reference materials and other resources whilst completing the questions. Each set of questions must be completed and submitted by the due date (listed on the website in the document 'Schedule and Important dates for SURG_5021'), and before students proceed to the next module. Answers to each module contribute 12% to the final score for the Unit (total 60% for the 5 modules), and a multiple choice quiz to be completed in the final week of the UOS contributes 40% to the final score.
Abbas, Lichtman and Pillai, Cellular and Molecular Immunology, 7th edition, Saunders; Current transplantation literature - linked to online teaching materials. These are listed in the 'Recommended Reading' document for each module.