Progress in our ability to cure or delay cancer is rapidly accelerating. The prospects of patients with cancer have been revolutionised by the genetic, molecular and cellular study of cancers in individual patients. This research is also enabling a more sophisticated understanding of how sub-cellular processes and the many different types of cells in the body interact to support human life. Together we will look at the molecular and cellular origins of the behaviours of cancers: what drives accelerated cancer cell replication, their resistance to cell death and their ability to induce angiogenesis, local invasion and metastasis. We will examine genomic instability, dysregulated cellular metabolism and the role of inflammation and the immune system. We will analyse these behaviours and their relevance to cancer therapy. You will work independently and in groups in face-to-face and online learning activities. You will deepen your knowledge of molecular and cellular biology and hone the intellectual and practical skills required to equip you to participate in the latest developments to improve survival and health for all cancer patients. Upon completion, you will have developed the skills required to launch your career in cancer research, clinical and diagnostic cancer services and/or the corporate system that supports the prevention, diagnosis and treatment of cancer.
Online lecturettes, book club, workshops with experts and advanced practicals (~4-6h per week)
Attendance and participation (10%), development of online learning resources (20%), Research Proposal (25%), Practical Assessment (15%) and exam (30%)
Resources on the LMS + the following article, book and textbook: Hanahan and Weinberg (2011) Hallmarks of Cancer: The Next Generation. Cell 144 The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee Robert A Weinberg. The Biology of Cancer, 2nd Edition
AMED3001 or AMED3901
BCMB2001 or BCMB2901 or MEDS2003