Without cells, life as we know it would not exist. These dynamic assemblies, packed with biological molecules are constantly in action. But how do cells work? Why is the food that you eat so important for cellular function? How is information transmitted from generation to generation? What happens as a result of disease or genetic mutation? In this unit of study you will learn how cells work at the molecular level, with an emphasis on human biochemistry and molecular biology. We will focus initially on cellular metabolism and how cells extract and store energy from fuels like fats and carbohydrates, how fuel use is modulated in response to exercise, starvation and disease, and how other key metabolites are processed. Then we will explore how genetic information is regulated in eukaryotes, including replication, transcription and translation, and molecular aspects of the cell cycle, mitosis and meiosis. Our practicals, along with other guided and online learning sessions will introduce you to widely applied and cutting-edge tools that are essential for modern biochemistry and molecular biology. By the end of this unit you will be equipped with foundational skills and knowledge to support your studies in the medical and life sciences.
Three lectures per week; one 4-hour practical session and 1 h tutorial per fortnight
Group presentation (5%), In-class continuous assessment (25%), PeerWise MCQ design (10%), ELMA design essay and interpretation (10%), final exam (50%)
Canvas, ELN Peerwise Site, Blackboard LMS Textbook: Biochemistry - Berg, Tymoczko, Gatto, Stryer 8th Ed or higher Wikipedia
6p from (BIOL1XX7 or MBLG1XX1) and 6cp of (CHEM1XX1 or CHEM1903)Prohibitions
BCHM2072 or BCHM2972 or MBLG2071 or MBLG2971 or BMED2405 or BCMB2001 or BCMB2901 or BMED2804