Drug Discovery and Design B goes beyond the basics to help students develop a deeper understanding of how drugs work, and how to discover and design new drugs. How drugs are transformed by metabolism is explored, with a particular focus on the factors which influence metabolism and pharmacogenetics. A problem-based learning approach will be used for the prediction of drug metabolite structures from physical, chemical, biochemical and spectroscopic data. Elements of statistics, stereochemistry, drug design, drug metabolism, and drug mechanism of action are integrated to explore the pathway from drug discovery and design to clinical application.
3x1hr lectures/week, 2x1hr mathematics tutorials/semester, 7x3hr workshops/semester
2hr exam (50%), quizzes (2x10%), metabolism assessments (3x10%)
G L Patrick (2013) An Introduction to Medicinal Chemistry, 5th Edition, Oxford University Press
(CHEM1611 or CHEM11X2 or CHEM19X2 or CHEM1904) and (CHEM1612 or CHEM11X1 or CHEM19X1 or CHEM1903) and PHAR1812.Co-requisites