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About the centre

A world-first centre tackling substance use and mental disorders
The Matilda Centre for Research in Mental Health and Substance Use is a multidisciplinary research centre committed to improving the health and wellbeing of people affected by co-occurring substance use and mental disorders.

Established in 2018, the Matilda Centre for Research in Mental Health and Substance Use aims to generate innovative and workable solutions to address substance use and mental disorders, which are currently the leading global causes of burden and disease in young people.

We work closely with research collaborators to share skills, synergise data and harness new technologies to develop and trial innovative prevention and early-intervention programs for co-occurring substance use and mental disorders.

We’re committed to

  • bringing together globally recognised researchers with a shared commitment to the prevention, early intervention and treatment of mental and substance use disorders
  • leading research to build the evidence base for a thriving and empowered younger generation
  • engaging with decision-makers and people with lived experience to enact real change
  • acting as a focal point and link between University of Sydney researchers, policy leaders and clinicians.

We facilitate collaboration

Our people are leading Australian and international researchers in addiction, mental health and youth health and our work builds dynamic, creative and global collaborations.

We invite those who share our mission to find workable solutions to prevent and treat comorbid mental health and substance use disorders to contact us.

We’re supervisors and mentors too

As leaders in our fields, we are proud to be educating a new generation of researchers, practitioners and teachers so that they too can think differently about substance use and mental health disorders.

We offer a range of opportunities for research students and early career researchers to study or work with us and receive mentorship from our internationally recognised researchers.

We can help you upskill

We also offer a range of training programs and resources for clinicians, school staff, families and the community to facilitate knowledge exchange around mental health and substance use, with the aim of improving support and changing lives.


Whether you’re looking to find out more about our current research, you want to partner or collaborate with us or learn more about our people, we look forward to hearing from you.

Join us in our mission to help youth across the globe who are struggling with substance use or mental health by getting in touch.