Professor Kirsten Morley
Prof Morley is the Director of the Addiction Treatment Research Theme at the Edith Collins Centre, Specialty of Addiction Medicine which is based at Royal Prince Alfred Hospital. She is also the Addiction Medicine Research Lead for the Institue of Academic Medicine.
Addiciton Medicine, Psychiatry
Substance Use, Alcohol Use Disorder, Neuroimaging, Mental Disorders, Self-harm, Mental Health, Comorbidity, Treatment, Translation, Implementation Science, Clinical Psychology, Psychedelic-assisted Therapy
Unit Coordinator + Curriculum Developer:
MD Year 2 Drug & Alcohol (Medicine),
Population Mental health PUBH5225 (Public Health)
Lecturer:
Masters of Brain and Mind Science (BMC)
MD Year 1 Alcohol & Health (Medicine)
Supervisor:
MPH Capstone Projects, MD Projects, PhD, MPhil, BMC Masters
Clinical stream: psychedelic-assisted therapies including MDMA for the treatment of alcohol use disorder and post traumatic stress disorder and Psilocybin for alcohol use disorder, exploring neurobiological basis of the treatment of alcohol use disorder via fMRI modalities, neurocircuitry of emotional regulation in alcohol use disorder, exploring novel strategies in treatment of alcohol use disorder
Translational stream: improving management of comorbid mental illness and substance use using an integrated approach (NSW Health), developing a shared care pathway for the treatment of alcohol dependence in primary care (NHMRC), nationwise patterns of treatment utilisation
Project title | Research student |
---|---|
Understanding the relationship between MDMA mental health and addiction and the implications for novel psychedelic treatments | Zachary BRYANT |
Oxidative stress and cognitive impairment in alcohol use disorder and the neuroprotective role of antioxidant treatment. | Kristiane DUNBAR |
Neural substrates underpinning co-occurring post-traumatic stress disorder and alcohol use disorder. | Ellen TOWERS |
Investigation of the psychedelic substances psilocybin and methylenedioxymethamphetamine (MDMA) in the treatment of alcohol use disorder | Josh WATT |
Understanding the Mechanisms of Punishment Insensitivity and Their Implications for Treating Alcohol Use Disorder | Liz ZENG |
Publications
Book Chapters
- Haber, P., Lintzeris, N., Morley, K. (2009). Pharmacotherapies for alcohol dependence. In Paul Haber, Elizabeth Proude, Nick Lintzeris & Olga Lopatko (Eds.), Guidelines for the Treatment of Alcohol Problems, (pp. 93-106). Australia: Commonwealth of Australia.
Journals
- Arunogiri, S., Morley, K. (2024). Commentary on Aubin et al.: Could combination medication approaches target mental health comorbidity in the context of alcohol use disorder? Addiction, 119(7), 1224-1225. [More Information]
- Higginbotham, B., Perez, J., Louie, E., Haber, P., Lubman, D., Arunogiri, S., Chatterton, M., Morley, K. (2024). Economic evaluations of alcohol pharmacotherapy: Systematic review of economic evaluations of pharmacotherapy for the treatment of alcohol use disorder. Australian and New Zealand Journal of Psychiatry, 58(2), 117-133. [More Information]
- Conigrave, J., Lee, K., Dobbins, T., Wilson, S., Padarian Campusano, J., Ivers, R., Morley, K., Haber, P., Vnuk, J., Marshall, K., Conigrave, K. (2024). No improvement in AUDIT-C screening and brief intervention rates among wait-list controls following support of Aboriginal Community Controlled Health Services: evidence from a cluster randomised trial. BMC Health Services Research, 24(1). [More Information]
Conferences
- Morley, K., Haber, P., Sitharthan, G., Tucker, P., Sitharthan, T. (2012). Clinical Predictors of Suicidal Behaviour Among Patients with Alcohol and/or Substance Abuse and Suicide Risk. APSAD Conference, Australasian Professional Society on Alcohol and other Drugs, Melbourne.
2024
- Arunogiri, S., Morley, K. (2024). Commentary on Aubin et al.: Could combination medication approaches target mental health comorbidity in the context of alcohol use disorder? Addiction, 119(7), 1224-1225. [More Information]
- Higginbotham, B., Perez, J., Louie, E., Haber, P., Lubman, D., Arunogiri, S., Chatterton, M., Morley, K. (2024). Economic evaluations of alcohol pharmacotherapy: Systematic review of economic evaluations of pharmacotherapy for the treatment of alcohol use disorder. Australian and New Zealand Journal of Psychiatry, 58(2), 117-133. [More Information]
- Conigrave, J., Lee, K., Dobbins, T., Wilson, S., Padarian Campusano, J., Ivers, R., Morley, K., Haber, P., Vnuk, J., Marshall, K., Conigrave, K. (2024). No improvement in AUDIT-C screening and brief intervention rates among wait-list controls following support of Aboriginal Community Controlled Health Services: evidence from a cluster randomised trial. BMC Health Services Research, 24(1). [More Information]
2023
- Sullivan, A., Ridley, N., Monds, L., Logberger, W., Hurzeler, T., Morley, K. (2023). Assessing the validity of the Wechsler Adult Intelligence Scale (WAIS-IV) in predicting completion in a long-term residential rehabilitation for substance use problems. Applied Neuropsychology. Adult, 30(5), 561-566. [More Information]
- Adams, C., Perry, N., Conigrave, J., Hurzeler, T., Stevens, J., Yacou Dunbar, K., Sweeney, A., Lee, K., Sutherland, G., Haber, P., Morley, K. (2023). Central markers of neuroinflammation in alcohol use disorder: A meta-analysis of neuroimaging, cerebral spinal fluid, and postmortem studies. Alcoholism: Clinical and Experimental Research, 47(2), 197-208. [More Information]
- Louie, E., Giannopoulos, V., Uribe Guajardo, M., Wood, K., Teesson, M., Childs, S., Baillie, A., Haber, P., Morley, K. (2023). Geographical variation in implementation of the Pathways to Comorbidity Care program in Australian drug and alcohol services. JBI Database of Systematic Reviews and Implementation Reports, 21(2), 186-193. [More Information]
2022
- Josifovski, N., Shand, F., Morley, K., Chia, J., Henshaw, R., Petrie, K., Reda, B., Li, E., Theobald, A., Onie, S., Haber, P., et al (2022). A pilot study of a text message and online brief contact intervention following self-harm or a suicide attempt: A mixed methods evaluation. General Hospital Psychiatry, 76, 2023-02-01 00:00:00. [More Information]
- Merrick, T., Louie, E., Cleary, M., Molloy, L., Baillie, A., Haber, P., Morley, K. (2022). A systematic review of the perceptions and attitudes of mental health nurses towards alcohol and other drug use in mental health clients. International Journal of Mental Health Nursing, 31(6), 1373-1389. [More Information]
- Maddern, X., Walker, L., Campbell, E., Arunogiri, S., Haber, P., Morley, K., Manning, V., Millan, E., McNally, G., Lubman, D., et al (2022). Can we enhance the clinical efficacy of cognitive and psychological approaches to treat substance use disorders through understanding their neurobiological mechanisms? Neuroscience and Biobehavioral Reviews, 142. [More Information]
2021
- Mason, A., Jang, K., Morley, K., Scarf, D., Collings, S., Riordan, B. (2021). A Content Analysis of Reddit Users' Perspectives on Reasons for Not following through with a Suicide Attempt. CyberPsychology, Behavior, and Social Networking, 24(10), 642-647. [More Information]
- Louie, E., Barrett, E., Baillie, A., Haber, P., Morley, K. (2021). A systematic review of evidence-based practice implementation in drug and alcohol settings: applying the consolidated framework for implementation research framework. Implementation Science, 16(1), 22-1-22-29. [More Information]
- Giannopoulos, V., Morley, K., Haber, P. (2021). Alcohol Use and misuse during the COVID-19 pandemic. Medicine Today, 22(4), 14-20.
2020
- Adams, C., Conigrave, J., Lewohl, J., Haber, P., Morley, K. (2020). Alcohol use disorder and circulating cytokines: A systematic review and meta-analysis. Brain, Behavior, and Immunity, 89, 501-512. [More Information]
- Logberger, W., Baillie, A., Haber, P., Morley, K. (2020). Baclofen modulates cardiovascular responses to appetitive cues in treatment-seeking alcohol use disorder individuals. Human Psychopharmacology-Clinical and Experimental, 35(2), e2722. [More Information]
- Morley, K., Lagopoulos, J., Logberger, W., Baillie, A., Adams, C., Haber, P. (2020). Brain GABA levels are reduced in alcoholic liver disease: A proton magnetic resonance spectroscopy study. Addiction Biology, 25(1), e12702. [More Information]
2019
- Sheynin, J., Myers, C., Ghafar, F., Morris, A., Morley, K., Haber, P., Moustafa, A. (2019). A pilot study of escape, avoidance, and approach behaviors in treated alcohol-dependent males. Journal of Clinical and Experimental Neuropsychology, 41(6), 601-614. [More Information]
- Jamshidi, N., Morley, K., Cairns, R., Dawson, A., Haber, P. (2019). A Review of Baclofen Overdoses in Australia: Calls to a Poisons Information Centre and a Case Series. Alcohol and Alcoholism, 54(1), 73-78. [More Information]
- Rombouts, S., Baillie, A., Haber, P., Morley, K. (2019). Clinical Predictors of Response to Baclofen in the Treatment of Alcohol use Disorder: Results from the BacALD Trial. Alcohol and Alcoholism, 54(3), 272-278. [More Information]
2018
- Agabio, R., Sinclair, J., Addolorato, G., Aubin, H., Beraha, E., Caputo, F., Chick, J., de La Selle, P., Franchitto, N., Haber, P., Morley, K., et al (2018). Baclofen for the treatment of alcohol use disorder: the Cagliari Statement. The Lancet Psychiatry, 5(12), 957-960. [More Information]
- Morley, K., Baillie, A., Fraser, I., Furneaux-Bate, A., Dore, G., Roberts, M., Abdalla, A., Phung, N., Haber, P. (2018). Baclofen in the treatment of alcohol dependence with or without liver disease: multisite, randomised, double-blind, placebo-controlled trial. British Journal of Psychiatry, 212(6), 362-369. [More Information]
- Heng, S., Jamshidi, N., Baillie, A., Louie, E., Dore, G., Phung, N., Haber, P., Morley, K. (2018). Baclofen Response in Alcohol Dependent Patients Concurrently Receiving Antidepressants: Secondary Analysis From the BacALD Study. Frontiers in Psychiatry, 9(576), 1-7. [More Information]
2017
- Larsen, M., Shand, F., Morley, K., Batterham, P., Petrie, K., Reda, B., Berrouiguet, S., Haber, P., Carter, G., Christensen, H. (2017). A Mobile Text Message Intervention to Reduce Repeat Suicidal Episodes: Design and Development of Reconnecting After a Suicide Attempt (RAFT). JMIR Mental Health, 4(4), 1-9. [More Information]
- Myers, C., Rego, J., Haber, P., Morley, K., Beck, K., Hogarth, L., Moustafa, A. (2017). Learning and generalization from reward and punishment in opioid addiction. Behavioural Brain Research, 317, 122-131. [More Information]
- Morley, K., Cornish, J., Faingold, A., Wood, K., Haber, P. (2017). Pharmacotherapeutic agents in the treatment of methamphetamine dependence. Expert Opinion on Investigational Drugs, 26(5), 563-578. [More Information]
2016
- Freyer, C., Morley, K., Haber, P. (2016). Alcohol use disorders in Australia. Internal Medicine Journal, 46(11), 1259-1268. [More Information]
- Morley, K., Baillie, A., Leung, S., Sannibale, C., Teesson, M., Haber, P. (2016). Is Specialized Integrated Treatment for Comorbid Anxiety, Depression and Alcohol Dependence Better than Treatment as Usual in a Public Hospital Setting? Alcohol and Alcoholism, 51(4), 402-409. [More Information]
- Morley, K., Logge, W., Pearson, S., Baillie, A., Haber, P. (2016). National trends in alcohol pharmacotherapy: findings from an Australian claims database. Drug and Alcohol Dependence, 166, 254-257. [More Information]
2014
- Morley, K., Baillie, A., Leung, S., Addolorato, G., Leggio, L., Haber, P. (2014). Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety. Alcohol and Alcoholism, 49(6), 654-660. [More Information]
- Hunt, G., Siegfried, N., Morley, K., Sitharthan, T., Cleary, M. (2014). Psychosocial interventions for people with both severe mental illness and substance misuse. Schizophrenia Bulletin, 40(1), 18-20. [More Information]
- Morley, K., Sitharthan, G., Haber, P., Tucker, P., Sitharthan, T. (2014). The Efficacy of an Opportunistic Cognitive Behavioral Intervention Package (OCB) on Substance Use and Comorbid Suicide Risk: A Multisite Randomized Controlled Trial. Journal of Consulting and Clinical Psychology, 82(1), 130-140. [More Information]
2013
- Morley, K., Baillie, A., Sannibale, C., Teesson, M., Haber, P. (2013). Integrated care for comorbid alcohol dependence and anxiety and/or depressive disorder: study protocol for an assessor-blind, randomized controlled trial. Addiction Science & Clinical Practice, 8, 1-8. [More Information]
- Hunt, G., Siegfried, N., Morley, K., Sitharthan, T., Cleary, M. (2013). Psychosocial interventions for people with both severe mental illness and substance misuse. Cochrane Database of Systematic Reviews, 2013 (10), 1-258. [More Information]
- Morley, K., Leung, S., Baillie, A., Haber, P. (2013). The efficacy and biobehavioural basis of baclofen in the treatment of alcoholic liver disease (BacALD): Study protocol for a randomised controlled trial. Contemporary Clinical Trials, 36(2), 348-355. [More Information]
2012
- Morley, K., Haber, P., Sitharthan, G., Tucker, P., Sitharthan, T. (2012). Clinical Predictors of Suicidal Behaviour Among Patients with Alcohol and/or Substance Abuse and Suicide Risk. APSAD Conference, Australasian Professional Society on Alcohol and other Drugs, Melbourne.
- Morley, K., Haber, P., Morgan, M., Samara, F. (2012). Pericyazine in the treatment of cannabis dependence in general practice: a naturalistic pilot trial. Substance Abuse and Rehabilitation, 3, 43-47. [More Information]
2010
- Morley, K., Teesson, M., Sannibale, C., Baillie, A., Haber, P. (2010). Clinical Predictors of Outcome from an Australian Pharmacological Relapse Prevention Trial. Alcohol and Alcoholism, 45, 520-526. [More Information]
- Baillie, A., Stapinski, L., Crome, E., Morley, K., Sannibale, C., Haber, P., Teesson, M. (2010). Some new directions for research on psychological interventions for comorbid anxiety and substance use disorders. Drug and Alcohol Review, 29(5), 518-524. [More Information]
2009
- Colagiuri, B., Morley, K., Boakes, R., Haber, P. (2009). Expectancy in double-blind placebo-controlled trials: an example from alcohol dependence. Psychotherapy and Psychosomatics, 78(3), 167-171. [More Information]
- Haber, P., Lintzeris, N., Morley, K. (2009). Pharmacotherapies for alcohol dependence. In Paul Haber, Elizabeth Proude, Nick Lintzeris & Olga Lopatko (Eds.), Guidelines for the Treatment of Alcohol Problems, (pp. 93-106). Australia: Commonwealth of Australia.
- Morley, K., Teesson, M., Sannibale, C., Haber, P. (2009). Sample bias from different recruitment strategies in a randomised controlled trial for alcohol dependence. Drug and Alcohol Review, 28(3), 222-229. [More Information]
2008
- Richardson, K., Baillie, A., Reid, S., Morley, K., Teesson, M., Sannibale, C., Weltman, M., Haber, P. (2008). Do acamprosate or naltrexone have an effect on daily drinking by reducing craving for alcohol? Addiction, 103(6), 953-959. [More Information]
- Thomson, C., Morley, K., Teesson, M., Sannibale, C., Haber, P. (2008). Issues with recruitment to randomised controlled trials in the drug and alcohol field: a literature review and Australian case study. Drug and Alcohol Review, 27(2), 115-122. [More Information]
2006
- Richardson, K., Reid, S., Morley, K., Teesson, M., Sannibale, C., Weltman, M., Baillie, A., Haber, P. (2006). The effects of alcohol and naltrexone on craving and alcohol consumption. Alcoholism: Clinical and Experimental Research, 30(s2), 169A-169A.
- Teesson, M., Morley, K., Reid, S., Sannibale, C., Thomson, C., Richardson, K., Haber, P. (2006). The influence of depression on pharmacotherapy for alcohol dependence. Alcoholism: Clinical and Experimental Research, 30(s2), 68A-68A.
2005
- Morley, K., Arnold, J., McGregor, I. (2005). Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29(5), 648-657. [More Information]
2004
- Morley, K., Li, K., Hunt, G., Mallet, P., McGregor, I. (2004). Cannabinoids Prevent The Acute Hyperthermia And Partially Protect Against The 5-Ht Depleting Effects Of Mdma ('Ecstasy') In Rats. Neuropharmacology, 46(7), 954-965. [More Information]
- Morley, K., Cornish, J., Li, K., McGregor, I. (2004). Preexposure To Mdma ("Ecstasy") Delays Acquisition But Facilitates Mdma-Induced Reinstatement Of Amphetamine Self-Administration Behavior In Rats. Pharmacology, Biochemistry and Behavior, 79(2), 331-342. [More Information]
2003
- Cornish, J., Shahnawaz, Z., Thompson, M., Wong, S., Morley, K., Hunt, G., McGregor, I. (2003). Heat increases 3,4-methylenedioxymethamphetamine self-administration and social effects in rats. European Journal of Pharmacology, 482(1-3), 339-341. [More Information]
- McGregor, I., Gurtman, C., Morley, K., Clemens, K., Li, K., Blokland, A., Cornish, J., Hunt, G. (2003). Increased anxiety and "depressive" symptoms months after MDMA ("ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes. Psychopharmacology, 168(4), 465-474. [More Information]
- Gallate, J., Morley, K., Ambermoon, P., McGregor, I. (2003). The consequences of beer consumption in rats: acute anxiolytic and ataxic effects and withdrawal-induced anxiety. Psychopharmacology, 166(1), 51-60. [More Information]
2002
- Gurtman, C., Morley, K., Li, K., Hunt, G., McGregor, I. (2002). Increased anxiety in rats after 3,4-methylenedioxymethamphetamine: association with serotonin depletion. European Journal of Pharmacology, 446(1-3), 89-96. [More Information]
2001
- Morley, K., Gallate, J., Hunt, G., McGregor, I., Mallet, P. (2001). Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("Ecstasy"). European Journal of Pharmacology, 433(1), 91-99. [More Information]
Selected Grants
2023
- Rewarding Research 2024, Morley K, Faculty of Medicine and Health/FMH Rewarding Research Success
2022
- Making it easier for Aboriginal and Torres Strait Islander primary health care services to screen for risky drinking and provide tailored feedback: adapting the Grog Survey App, Lee K, Conigrave J, Wilson S, Hayman N, Conigrave K, Percival N, Chikritzhs T, Dawson A, Tracy M, Morley K, Doyle M, Fitts M, Weatherall T, Department of Health and Aged Care (Federal - administered by NHMRC)/2021 Primary Health Care Digital Innovations