Professor Michael Barnett
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Professor Michael Barnett

Professor of Neurology
Central Clinical School, Sydney Medical School, Faculty of Medicine and Health
Phone
+61 2 9351 0730
Fax
+61 2 9351 0653
Professor Michael Barnett

Selected publications

Publications

Books

  • Malik, O., Donnelly, A., Barnett, M. (2014). Fast Facts: Multiple Sclerosis 3rd edition. Oxford: Health Press Limited.

Journals

  • Riley, N., Wong, E., Walker, R., Drudge, C., Nelson, M., Barnett, M. (2024). Comparative efficacy of ofatumumab versus oral therapies for relapsing multiple sclerosis patients using propensity score analyses and simulated treatment comparisons. Therapeutic Advances in Neurological Disorders, 17. [More Information]
  • Klistorner, S., Barnett, M., Klistorner, A. (2024). Longitudinal enlargement of choroid plexus is associated with chronic lesion expansion and neurodegeneration in RRMS patients. Multiple Sclerosis Journal. [More Information]
  • Kyle, K., Peters, J., Jonker, B., Barnett, Y., Maamary, J., Barnett, M., Maller, J., Wang, C., Tisch, S. (2024). Magnetic Resonance–Guided Focused Ultrasound for Treatment of Essential Tremor: Ventral Intermediate Nucleus Ablation Alone or Additional Posterior Subthalamic Area Lesioning? Movement Disorders Clinical Practice, 11(5), 504-514. [More Information]

Conferences

  • Tang, Z., Cabezas Grebol, M., D'Souza, A., Calamante, F., Liu, D., Barnett, M., Wang, C., Cai, W. (2022). Diffusion MRI Fibre Orientation Distribution Inpainting. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), : Springer Verlag.
  • Tang, Z., Cabezas Grebol, M., Liu, D., Barnett, M., Cai, W., Wang, C. (2021). LG-Net: Lesion Gate Network for Multiple Sclerosis Lesion Inpainting. 24th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2021), Cham: Springer Nature. [More Information]
  • Wang, D., Wang, C., Masters, L., Barnett, M. (2020). Masked Multi-Task Network for Case-Level Intracranial Hemorrhage Classification in Brain CT Volumes. 23rd International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2020), Cham: Springer. [More Information]

2024

  • Riley, N., Wong, E., Walker, R., Drudge, C., Nelson, M., Barnett, M. (2024). Comparative efficacy of ofatumumab versus oral therapies for relapsing multiple sclerosis patients using propensity score analyses and simulated treatment comparisons. Therapeutic Advances in Neurological Disorders, 17. [More Information]
  • Klistorner, S., Barnett, M., Klistorner, A. (2024). Longitudinal enlargement of choroid plexus is associated with chronic lesion expansion and neurodegeneration in RRMS patients. Multiple Sclerosis Journal. [More Information]
  • Kyle, K., Peters, J., Jonker, B., Barnett, Y., Maamary, J., Barnett, M., Maller, J., Wang, C., Tisch, S. (2024). Magnetic Resonance–Guided Focused Ultrasound for Treatment of Essential Tremor: Ventral Intermediate Nucleus Ablation Alone or Additional Posterior Subthalamic Area Lesioning? Movement Disorders Clinical Practice, 11(5), 504-514. [More Information]

2023

  • Barnett, M., Wang, D., Beadnall, H., Bischof, A., Brunacci, D., Butzkueven, H., Brown, J., Cabezas Grebol, M., Das, T., Dugal, T., Klistorner, A., Kyle, K., Tang, Z., Zhan, G., Wang, C., et al (2023). A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis. npj Digital Medicine, 6(1). [More Information]
  • Hartung, H., Cree, B., Barnett, M., Meuth, S., Bar-Or, A., Steinman, L. (2023). Bioavailable central nervous system disease-modifying therapies for multiple sclerosis. Frontiers in Immunology, 14. [More Information]
  • Klistorner, S., van der Walt, A., Barnett, M., Butzkueven, H., Kolbe, S., Parratt, J., Yiannikas, C., Klistorner, A. (2023). Choroid plexus volume is enlarged in clinically isolated syndrome patients with optic neuritis. Multiple Sclerosis Journal. [More Information]

2022

  • Sesel, A., Sharpe, L., Beadnall, H., Barnett, M., Szabo, M., Naismith, S. (2022). A randomized controlled trial of a web-based mindfulness programme for people with MS with and without a history of recurrent depression. Multiple Sclerosis Journal, 28(9), 1392-1401. [More Information]
  • D'Souza, A., Wang, C., Tu, S., Soligo, D., Kiernan, M., Barnett, M., Calamante, F. (2022). A robust framework for characterising diffusion metrics of the median and ulnar nerves: Exploiting state-of-the-art tracking methods. Journal of the Peripheral Nervous System, 27(1), 67-83. [More Information]
  • Klistorner, S., Barnett, M., Parratt, J., Yiannikas, C., Graham, S., Klistorner, A. (2022). Choroid plexus volume in multiple sclerosis predicts expansion of chronic lesions and brain atrophy. Annals of Clinical and Translational Neurology, 9(10), 1528-1537. [More Information]

2021

  • Khurana, V., Jithoo, R., Barnett, M. (2021). Aerospace Implications of Key Neurological Conditions. Aerospace Medicine and Human Performance, 92(2), 113-119. [More Information]
  • Merlo, D., Stankovich, J., Bai, C., Kalincik, T., Zhu, C., Gresle, M., Lechner-Scott, J., Kilpatrick, T., Barnett, M., Taylor, B., et al (2021). Association between cognitive trajectories and disability progression in patients with relapsing-remitting multiple sclerosis. Neurology, 97(20), E2020-E2031. [More Information]
  • Chaseling, G., Filingeri, D., Allen, D., Barnett, M., Vucic, S., Davis, S., Jay, O. (2021). Blunted sweating does not alter the rise in core temperature in people with multiple sclerosis exercising in the heat. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 320(3), 258-267. [More Information]

2020

  • Hartung, H., Mares, J., Barnett, M. (2020). Alemtuzumab: Rare serious adverse events of a high-efficacy drug. Multiple Sclerosis Journal, 26(6), 737-740. [More Information]
  • You, Y., Barnett, M., Yiannikas, K., Parratt, J., Matthews, J., Graham, S., Klistorner, A. (2020). Chronic demyelination exacerbates neuroaxonal loss in patients with MS with unilateral optic neuritis. Neurology: Neuroimmunology and Neuroinflammation, 7(3), 1-10. [More Information]
  • Fernández, O., Izquierdo, G., Aguera, E., Ramo, C., Hernandez, M., Silva, D., Walker, R., Butzkueven, H., Wang, C., Barnett, M. (2020). Comparison of first-line and second-line use of fingolimod in relapsing MS: The open-label EARLIMS study. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 6(3), 1-11. [More Information]

2019

  • Schweitzer, F., Laurent, S., Fink, G., Barnett, M., Reddel, S., Hartung, H., Warnke, C. (2019). Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis. Current Opinion In Neurology, 32(3), 305-312. [More Information]
  • Prain, K., Woodhall, M., Vincent, A., Ramanathan, S., Barnett, M., Bundell, C., Parratt, J., Silvestrini, R., Bukhari, W., Brilot-Turville, F., et al (2019). AQP4 Antibody Assay Sensitivity Comparison in the Era of the 2015 Diagnostic Criteria for NMOSD. Frontiers in Neurology, 10, 1-7. [More Information]
  • Gross, C., Meyer, C., Bhatia, U., Yshii, L., Kleffner, I., Bauer, J., Troscher, A., Schulte-Mecklenbeck, A., Herich, S., Schneider-Hohendorf, T., Parratt, J., Barnett, M., Buckland, M., Hardy, T., Reddel, S., Wiendl, H., et al (2019). CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome. Nature Communications, 10(1), 1-19. [More Information]

2018

  • Tang, Z., Wang, C., Hoang, P., Liu, S., Cai, W., Soligo, D., Oliver, R., Barnett, M., Fornusek, C. (2018). Automatic segmentation of thigh muscle in longitudinal 3D T1-weighted magnetic resonance (MR) images. Medical Image Computing and Computer-Assisted Intervention (MICCAI 2018) - First International Data Driven Treatment Response Assessment Workshop (DATRA 2018) and Third International Preterm, Perinatal, and Paediatric Image Analysis Workshop (PIPPI 2018), Cham: Springer Nature. [More Information]
  • Kalincik, T., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Lechner-Scott, J., Lugaresi, A., Prat, A., Girard, M., et al (2018). Cladribine versus fingolimod, natalizumab and interferon beta for multiple sclerosis. Multiple Sclerosis Journal, 24(12), 1617-1626. [More Information]
  • Ramanathan, S., Mohammad, S., Tantsis, E., Nguyen, T., Merheb, V., Fung, V., White, O., Broadley, S., Lechner-Scott, J., Vucic, S., Henderson, A., Barnett, M., Reddel, S., Brilot-Turville, F., Dale, R. (2018). Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination. Journal of Neurology, Neurosurgery and Psychiatry, 89(2), 127-137. [More Information]

2017

  • Filingeri, D., Chaseling, G., Hoang, P., Barnett, M., Davis, S., Jay, O. (2017). Afferent thermosensory function in relapsing-remitting Multiple Sclerosis following exercise-induced increases in body temperature. Experimental Physiology, 102(8), 887-893. [More Information]
  • Mathey, E., Garg, N., Park, S., Nguyen, T., Baker, S., Yuki, N., Yiannikas, K., Lin, C., Spies, J., Ghaoui, R., Barnett, M., Vucic, S., Pollard, J., Kiernan, M. (2017). Autoantibody responses to nodal and paranodal antigens in chronic inflammatory neuropathies. Journal of Neuroimmunology, 309, 41-46. [More Information]
  • Stewart, T., Spelman, T., Havrdova, E., Horakova, D., Trojano, M., Izquierdo, G., Duquette, P., Girard, M., Prat, A., Vucic, S., Barnett, M., et al (2017). Contribution of different relapse phenotypes to disability in multiple sclerosis. Multiple Sclerosis Journal, 23(2), 266-276. [More Information]

2016

  • Garg, N., Yuki, N., Park, S., Barnett, M., Kiernan, M. (2016). Acute bulbar, neck and limb weakness with monospecific anti-GT1a antibody: A rare localized subtype of Guillain-Barre sydnrome. Muscle and Nerve, 53(1), 143-146. [More Information]
  • Hardy, T., Reddel, S., Barnett, M., Palace, J., Lucchinetti, C., Weinshenker, B. (2016). Atypical inflammatory demyelinating syndromes of the CNS. The Lancet Neurology, 15(9), 967-981. [More Information]
  • Wang, C., Beadnall, H., Hatton, S., Bader, G., Tomic, D., Silva, D., Barnett, M. (2016). Automated brain volumetrics in multiple sclerosis: a step closer to clinical application. Journal of Neurology, Neurosurgery and Psychiatry, 87(7), 754-757. [More Information]

2015

  • Broadley, S., Barnett, M., Boggild, M., Brew, B., Butzkueven, H., Heard, R., Hodgkinson, S., Kermode, A., Lechner-Scott, J., Macdonell, R., Parratt, J., Reddel, S., Spies, J., Pollard, J., et al (2015). A new era in the treatment of multiple sclerosis. Medical Journal of Australia, 203(3), 139-141. [More Information]
  • Gu, B., Field, J., Dutertre, S., Ou, A., Kilpatrick, T., Lechner-Scott, J., Scott, R., Lea, R., Taylor, B., Stankovich, J., et al (2015). A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis. Human Molecular Genetics, 24(19), 5644-5654. [More Information]
  • Wang, C., Paling, D., Chen, L., Hatton, S., Lagopoulos, J., Aw, S., Kiernan, M., Barnett, M. (2015). Axonal conduction in multiple sclerosis: A combined magnetic resonance imaging and electrophysiological study of the medial longitudinal fasciculus. Multiple Sclerosis Journal, 21(7), 905-915. [More Information]

2014

  • Ramanathan, S., Reddel, S., Henderson, A., Parratt, J., Barnett, M., Gatt, P., Merheb, V., Kumaran, R., Pathmanandavel, K., Sinmaz, N., Yiannikas, K., Vucic, S., Stewart, G., Booth, D., Dale, R., Brilot-Turville, F., et al (2014). Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis. Neurology: Neuroimmunology and Neuroinflammation, 1(4), 1-12. [More Information]
  • Klistorner, A., Sriram, P., Vootakuru, N., Wang, C., Barnett, M., Garrick, R., Parratt, J., Levin, N., Raz, N., van der Walt, A., Masters, L., et al (2014). Axonal loss of retinal neurons in multiple sclerosis associated with optic radiation lesions. Neurology, 82(24), 2165-2172. [More Information]
  • Cordina, R., Grieve, S., Barnett, M., Lagopoulos, J., Malitz, N., Celermajer, D. (2014). Brain volumetric, regional cortical thickness and radiographic findings in adults with cyanotic congenital heart disease. NeuroImage: Clinical, 4, 319-325. [More Information]

2013

  • Klistorner, A., Garrick, R., Barnett, M., Graham, S., Arvind Srinivasan, H., Sriram, P., Yiannikas, C. (2013). Axonal loss in non-optic neuritis eyes of patients with multiple sclerosis linked to delayed visual evoked potential. Neurology, 80(3), 242-245. [More Information]
  • Verheul, F., Smolders, J., Trojano, M., Lepore, V., Zwanikken, C., Amato, M., Grand'Maison, F., Butzkueven, H., Marrosu, M., Duquette, P., Barnett, M., et al (2013). Fluctuations of MS births and UV-light exposure. Acta Neurologica Scandinavica, 127(5), 301-308. [More Information]
  • Lin, R., Charlesworth, J., Stankovich, J., Perreau, V., Brown, M., Taylor, B., Baxter, A., Kermode, A., Bahlo, M., Booth, D., Stewart, G., Barnett, M., Heard, R., et al (2013). Identity-by-Descent Mapping to Detect Rare Variants Conferring Susceptibility to Multiple Sclerosis. PloS One, 8(3), 1-8. [More Information]

2012

  • Meyniel, C., Spelman, T., Jokubaitis, V., Trojano, M., Izquierdo, G., Grand'Maison, F., Oreja-Guevara, C., Boz, C., Lugaresi, A., Girard, M., Barnett, M., et al (2012). Country, Sex, EDSS Change and Therapy Choice Independently Predict Treatment Discontinuation in Multiple Sclerosis and Clinically Isolated Syndrome. PloS One, 7(6), 1-8. [More Information]
  • Simon, N., Parratt, J., Barnett, M., Buckland, M., Gupta, R., Hayes, M., Masters, L., Reddel, S. (2012). Expanding the clinical, radiological and neuropathological phenotype of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Journal of Neurology, Neurosurgery and Psychiatry, 83(1), 15-22. [More Information]
  • Bien, C., Vincent, A., Barnett, M., Becker, A., Blumcke, I., Graus, F., Jellinger, K., Reuss, D., Ribalta, T., Schlegel, J., et al (2012). Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis. Brain, 135(Pt 5), 1622-1638. [More Information]

2011

  • Barnett, M., Chohan, G., Davies, L. (2011). Blurred vision and pain in the eye. Medical Journal of Australia, 195(6), 329-332. [More Information]
  • Ly, L., Barnett, M., Zheng, Y., Gulati, T., Prineas, J., Crossett, B. (2011). Comprehensive Tissue Processing Strategy for Quantitative Proteomics of Formalin-fixed Multiple Sclerosis Lesions. Journal of Proteome Research, 10(10), 4855-4868. [More Information]
  • Ahmed, R., Buckland, M., Davies, L., Halmagyi, G., Rogers, S., Oberste, M., Barnett, M. (2011). Enterovirus 71 meningoencephalitis complicating rituximab therapy. Journal of the Neurological Sciences, 305(1-2), 149-151. [More Information]

2010

  • Henderson, A., Barnett, M., Parratt, J. (2010). Reply. Annals of Neurology, 68(5), 768. [More Information]

2009

  • Sutton, I., Lahoria, R., Tan, I., Clouston, P., Barnett, M. (2009). CNS demyelination and quadrivalent HPV vaccination. Multiple Sclerosis: clinical and laboratory research, 15(1), 116-119. [More Information]
  • Barnett, M., Parratt, J., Cho, E., Prineas, J. (2009). Immunoglobulins and complement in postmortem multiple sclerosis tissue. Annals of Neurology, 65(1), 32-46. [More Information]
  • Barnett, M., Parratt, J., Pollard, J., Prineas, J. (2009). MS: Is it One Disease? The International M S Journal, 16(2), 57-65. [More Information]

2007

  • McLeod, J., Barnett, M., Macaskill, P., Williams, D. (2007). Long-term prognosis of multiple sclerosis in Australia. Journal of the Neurological Sciences, 256, 35-38. [More Information]

2006

  • Barnett, M., Henderson, A., Prineas, J. (2006). The macrophage in MS: just a scavenger after all? Pathology and pathogenesis of the acute MS lesion. Multiple Sclerosis: clinical and laboratory research, 12(2), 121-132. [More Information]
  • Patani, (., Barnett, M., Prineas, J. (2006). The pathology of impaired remyelination in multiple sclerosis. 189th Meeting of the Pathological Society of Great Britain and Ireland, United Kingdom: John Wiley & Sons.
  • Barnett, M., Sutton, I. (2006). The pathology of multiple sclerosis: a paradigm shift. Current Opinion In Neurology, 19(3), 242-247. [More Information]

2004

  • Barnett, M., Prineas, J. (2004). Relapsing And Remitting Multiple Sclerosis: Pathology Of The Newly Forming Lesion. Annals of Neurology, 55(4), 458-468. [More Information]

2003

  • Cordato, D., Herkes, G., Mather, L., Morgan, M. (2003). Barbiturates for acute neurological and neurosurgical emergencies – do they still have a role? Journal of Clinical Neuroscience, 10(3), 283-288. [More Information]
  • Chan, C., Fryer, J., Herkes, G., Prelog, K., Harrington, T. (2003). Fatal brain stem event complicating acute pancreatitis. Journal of Clinical Neuroscience, 10(3), 351-358. [More Information]
  • Barnett, M., Williams, D., Day, S., Macaskill, P., McLeod, J. (2003). Progressive increase in incidence and prevalence of multiple sclerosis in Newcastle, Australia: a 35-year study. Journal of the Neurological Sciences, 213(1-2), 1-6. [More Information]

2001

  • Iland, H., Barnett, M., Pollard, J., Supple, S. (2001). A spontaneous novel XK gene mutation in a patient with McLeod syndrome. British Journal of Haematology, 115, 369-372.

Selected Grants

2024

  • The Hallett Family & Goldman Sachs Neurological Research and Development Fund, Barnett M, GOLDMAN SACHS GIVES/Pulse Prize

2023

  • Rewarding Research 2024, Barnett M, Faculty of Medicine and Health/FMH Rewarding Research Success
  • Artificial intelligence to optimise the diagnosis of neuropathy, Barnett M, Faculty of Medicine and Health/Shared Research Support
  • Clinical imaging biomarkers for monitoring disease progression in an Australian cohort of patients with Susacs Syndrome, Hardy T, Barnett M, Beadnall H, Wang C, Ly L, Brain Foundation/Research Grants