2024

• Spiteri, A., Wishart, C., Pinget, G., Purohit, S., Macia, L., King, N., Niewold, P. (2024). NK cell profiling in West Nile virus encephalitis reveals potential metabolic basis for functional inhibition. Immunology and Cell Biology. [More Information]

2023

• Tan, J., Macia, L., Mackay, C. (2023). Dietary fiber and SCFAs in the regulation of mucosal immunity. Journal of Allergy and Clinical Immunology, 151(2), 361-370. [More Information]
• Sen, M., Ge, A., Liao, E., Gard, H., Ni, D., Macia, L., Piccio, L. (2023). Impact of a high fibre diet on immune cells and the multiple sclerosis animal model. Journal of Immunology, 210(Suppl 1). [More Information]
• Audo, R., Sanchez, P., Rivière, B., Mielle, J., Tan, J., Lukas, C., Macia, L., Morel, J., Immediato Daien, C. (2023). Rheumatoid arthritis is associated with increased gut permeability and bacterial translocation that are reversed by inflammation control. Rheumatology, 62(3), 1264-1271. [More Information]
• Audo, R., Sanchez, P., Riviere, B., Mielle, J., Tan, J., Lukas, C., Macia, L., Morel, J., Daien, C. (2023). Rheumatoid arthritis is associated with increased gut permeability and bacterial translocation which are reversed by inflammation control. Rheumatology, 62, 1264-1271. [More Information]
• Spiteri, A., Wishart, C., Ni, D., Viengkhou, B., Macia, L., Hofer, M., King, N. (2023). Temporal tracking of microglial and monocyte single-cell transcriptomics in lethal favivirus infection. Springer Nature, 11(60). [More Information]

2022

• Eberhard, J., Ruiz, K., Tan, J., Vidanelage, T., Khan, S., Inan Eroglu, E., Adler, C., Simpson, S., Le Couteur, D., Raubenheimer, D., Macia, L., Gosby, A., Ribeiro, R. (2022). A randomized clinical trial to investigate the effect of dietary protein sources on periodontal health. Journal of Clinical Periodontology, 49(4), 388-400. [More Information]
• Rempenault, C., Mielle, J., Schreiber, K., Corbeau, P., Macia, L., Combe, B., Morel, J., Daien, C., Audo, R. (2022). CXCR5/CXCL13 pathway, a key driver for migration of regulatory B10 cells, is defective in patients with rheumatoid arthritis. Rheumatology, 61(5), 2185-2196. [More Information]
• Simpson, R., Shanahan, E., Batten, M., Reijers, I., Read, M., Da Silva, I., Versluis, J., Ribeiro, R., Angelatos, A., Tan, J., Adhikari, C., Menzies, A., Saw, R., Gonzalez, M., Shannon, K., Spillane, A., Velickovic, R., Macia, L., Holmes, A., Wilmott, J., Scolyer, R., Long, G., et al (2022). Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome. Nature Medicine, 28(11), 2344-2352. [More Information]
• Tan, J., Ni, D., Taitz, J., Pinget, G., Read, M., Senior, A., Wali, J., Elnour, R., Shanahan, E., Wu, H., Chadban, S., Nanan, R., King, N., Grau, G., Simpson, S., Macia, L. (2022). Dietary protein increases T-cell-independent sIgA production through changes in gut microbiota-derived extracellular vesicles. Nature Communications, 13(1), 4336-1-4336-15. [More Information]
• Pinget, G., Tan, J., Ni, D., Taitz, J., Daien, C., Mielle, J., Moore, R., Stanley, D., Simpson, S., King, N., Macia, L. (2022). Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development. Cell Reports, 40(7). [More Information]
• Mielle, J., Morel, J., Elhmioui, J., Combe, B., Macia, L., Dardalhon, V., Taylor, N., Audo, R., Daien, C. (2022). Glutamine promotes the generation of B10+ cells via the mTOR/GSK3 pathway. European Journal of Immunology, 52(3), 418-430. [More Information]
• Ni, D., Tan, J., Niewold, P., Spiteri, A., Pinget, G., Stanley, D., King, N., Macia, L. (2022). Impact of Dietary Fiber on West Nile Virus Infection. Frontiers in Immunology, 13, 784486-1-784486-9. [More Information]
• Spiteri, A., Ni, D., Ling, Z., Macia, L., Campbell, I., Hofer, M., King, N. (2022). PLX5622 Reduces Disease Severity in Lethal CNS Infection by Off-Target Inhibition of Peripheral Inflammatory Monocyte Production. Frontiers in Immunology, 13, 851556. [More Information]
• Tan, J., Taitz, J., Sun, S., Langford, L., Ni, D., Macia, L. (2022). Your Regulatory T Cells Are What You Eat: How Diet and Gut Microbiota Affect Regulatory T Cell Development. Frontiers in Nutrition, 9. [More Information]

2021

• Tan, J., Ni, D., Wali, J., Cox, D., Pinget, G., Taitz, J., Daien, C., Senior, A., Read, M., Simpson, S., King, N., Macia, L. (2021). Dietary carbohydrate, particularly glucose, drives B cell lymphopoiesis and function. iScience, 24(8), 102835. [More Information]
• Macia, L., Galy, O., Nanan, R. (2021). Editorial: Modern Lifestyle and Health: How Changes in the Environment Impacts Immune Function and Physiology. Frontiers in Immunology, 12, 762166. [More Information]
• Liu, Y., Li, Y., Loh, Y., Singer, J., Zhu, W., Macia, L., Mackay, C., Wang, W., Chadban, S., Wu, H. (2021). Fiber Derived Microbial Metabolites Prevent Acute Kidney Injury Through G-Protein Coupled Receptors and HDAC Inhibition. Frontiers in Cell and Developmental Biology, 9, 648639. [More Information]
• Daien, C., Tan, J., Audo, R., Mielle, J., Quek, L., Krycer, J., Angelatos, A., Duraes, M., Pinget, G., Ni, D., Amian, M., Sierro, F., Parmar, A., Hoque, S., Gosby, A., Simpson, S., Ribeiro, R., Macia, L., et al (2021). Gut-derived acetate promotes B10 cells with antiinflammatory effects. JCI Insight, 6(7), e144156. [More Information]
• Tan, J., Ni, D., Ribeiro, R., Pinget, G., Macia, L. (2021). How changes in the nutritional landscape shape gut immunometabolism. Nutrients, 13(3), 1-36. [More Information]
• Wali, J., Milner, A., Luk, A., Pulpitel, T., Dodgson, T., Facey, H., Wahl, D., Kebede, M., Senior, A., Sullivan, M., Brandon, A., Yau, B., Lockwood, G., Koay, Y., Ribeiro, R., Solon-Biet, S., Bell-Anderson, K., O'Sullivan, J., Macia, L., Cooney, G., Cogger, V., Holmes, A., Raubenheimer, D., Le Couteur, D., Simpson, S., et al (2021). Impact of dietary carbohydrate type and protein–carbohydrate interaction on metabolic health. Nature Metabolism, 3(6), 810-828. [More Information]
• Yau, B., Naghiloo, S., Diaz Vegas, A., Carr, A., Van Gerwen, J., Needham, E., Jevon, D., Chen, S., Hoehn, K., Brandon, A., Macia, L., Cooney, G., Thorn, P., Larance, M., James, D., Humphrey, S., Kebede, M., et al (2021). Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet. iScience, 24(10), 103099. [More Information]
• Singer, J., Li, Y., Ying, T., Aouad, L., Gracey, D., Wyburn, K., Macia, L., Wu, H., Chadban, S. (2021). Protocol for a pilot single-centre, parallel-arm, randomised controlled trial of dietary inulin to improve gut health in solid organ transplantation: The DIGEST study. BMJ Open, 11(4). [More Information]
• Gao, Y., Nanan, R., Macia, L., Tan, J., Sominsky, L., Quinn, T., O'Hely, M., Ponsonby, A., Tang, M., Collier, F., et al (2021). The maternal gut microbiome during pregnancy and offspring allergy and asthma. Journal of Allergy and Clinical Immunology, 148(3), 669-678. [More Information]

2020

• Li, Y., Chen, X., Kwan, T., Loh, Y., Singer, J., Liu, Y., Ma, J., Tan, J., Macia, L., Mackay, C., Chadban, S., Wu, H. (2020). Dietary fiber protects against diabetic nephropathy through short-chain fatty acid-mediated activation of G protein-coupled receptors GPR43 and GPR109A. Journal of the American Society of Nephrology, 31(6), 1267-1281. [More Information]
• Wu, H., Singer, J., Kwan, T., Loh, Y., Wang, C., Tan, J., Li, Y., Lai, S., Macia, L., Alexander, S., Chadban, S. (2020). Gut microbial metabolites induce donor-specific tolerance of kidney allografts through induction of T regulatory cells by short-chain fatty acids. Journal of the American Society of Nephrology, 31(7), 1445-1461. [More Information]
• Macia, L., Nanan, R., Hosseini Beheshti, E., Grau, G. (2020). Host- and Microbiota-Derived Extracellular Vesicles, Immune Function, and Disease Development. International Journal of Molecular Sciences, 21(1), 1-18. [More Information]
• Pinget, G., Tan, J., Niewold, P., Mazur, E., Angelatos, A., King, N., Macia, L. (2020). Immune Modulation of Monocytes Dampens the IL-17+ gamma-delta T Cell Response and Associated Psoriasis Pathology in Mice. Journal of Investigative Dermatology, 140(12), 2398-2407.e1. [More Information]
• Vuillermin, P., O’Hely, M., Collier, F., Allen, K., Tang, M., Harrison, L., Carlin, J., Saffery, R., Ranganathan, S., Sly, P., Macia, L., et al (2020). Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring. Nature Communications, 11(1), 1-7. [More Information]
• Khanal, D., Lei, Q., Pinget, G., Cheong, D., Gautam, A., Yusoff, R., Su, B., Yamaguchi, S., Kondyurin, A., Knowles, J., Macia, L., Ramzan, I., Chrzanowski, W., et al (2020). The protein corona determines the cytotoxicity of nanodiamonds: implications of corona formation and its remodelling on nanodiamond applications in biomedical imaging and drug delivery. Nanoscale Advances, 2(10), 4798-4812. [More Information]

2019

• Hu, M., Eviston, D., Hsu, P., Marino, E., Chidgey, A., Nanan, B., Wong, K., Richards, J., Yap, Y., Collier, F., Quinton, A., Joung, S., Peek, M., Benzie, R., Macia, L., Nanan, R., et al (2019). Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia. Nature Communications, 10(1), 1-13. [More Information]
• Macia, L., Mackay, C. (2019). Dysfunctional microbiota with reduced capacity to produce butyrate as a basis for allergic diseases. Journal of Allergy and Clinical Immunology, 144(6), 1513-1515. [More Information]
• Xiang, M., Tan, J., Macia, L. (2019). Fatty Acids, Gut Bacteria, and Immune Cell Function. In Not known (Eds.), The Molecular Nutrition of Fats, (pp. 151-164). TBC. [More Information]
• Pinget, G., Tan, J., Janac, B., Kaakoush, N., Angelatos, A., O'Sullivan, J., Koay, Y., Sierro, F., Davis, J., Divakarla, S., Khanal, D., Chrzanowski, W., Macia, L., et al (2019). Impact of the Food Additive Titanium Dioxide (E171) on Gut Microbiota-Host Interaction. Frontiers in Nutrition, 6, 1-13. [More Information]
• Koay, Y., Wali, J., Luk, A., Macia, L., Cogger, V., Pulpitel, T., Wahl, D., Solon-Biet, S., Holmes, A., Simpson, S., O'Sullivan, J. (2019). Ingestion of resistant starch by mice markedly increases microbiome-derived metabolites. The FASEB Journal, 33(7), 8033-8042. [More Information]
• Ribeiro, R., Simpson, S., Le Couteur, D., Raubenheimer, D., Eberhard, J., Ruiz, K., Macia, L., Todorova, Y., Gosby, A. (2019). The nutrition for healthy living study: A randomised clinical trial assessing the effect of protein sources on healthy ageing. Nutrition and Healthy Aging, 5(1), 43-51. [More Information]

2018

• Mielle, J., Audo, R., Hahne, M., Macia, L., Combe, B., Daien, C. (2018). IL-10 producing B cells ability to induce regulatory T cells is maintained in rheumatoid arthritis. Frontiers in Immunology, 9(MAY), 1-11. [More Information]
• Simpson, S., Raubenheimer, D., Cogger, V., Macia, L., Solon-Biet, S., Le Couteur, D., George, J. (2018). The nutritional geometry of liver disease including non-alcoholic fatty liver disease (NAFLD). Journal of Hepatology, 68(2), 316-325. [More Information]

2017

• Daien, C., Pinget, G., Tan, J., Macia, L. (2017). Detrimental impact of microbiota-accessible carbohydrate-deprived diet on gut and immune homeostasis: An overview. Frontiers in Immunology, 8, 1-7. [More Information]
• Goverse, G., Molenaar, R., Macia, L., Tan, J., Erkelens, M., Konijn, T., Knippenberg, M., Cook, E., Hanekamp, D., et al (2017). Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells. Journal of Immunology, 198(5), 2172-2181. [More Information]
• Vieira, A., Galvao, I., Macia, L., Sernaglia, E., Vinolo, M., Garcia, C., Tavares, L., Amaral, F., Sousa, L., et al (2017). Dietary fiber and the short-chain fatty acid acetate promote resolution of neutrophilic inflammation in a model of gout in mice. Journal of Leukocyte Biology, 101(1), 275-284. [More Information]
• Marino, E., Richards, J., McLeod, K., Stanley, D., Yap, Y., Knight, J., McKenzie, C., Kranich, J., Oliveira, A., Macia, L., et al (2017). Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes. Nature Immunology, 18(5), 552-562. [More Information]
• Tan, J., McKenzie, C., Marino, E., Macia, L., Mackay, C. (2017). Metabolite-sensing G protein-coupled receptors-facilitators of diet-related immune regulation. Annual Review of Immunology, 35, 371-402. [More Information]
• Vuillermin, P., Macia, L., Nanan, R., Tang, M., Collier, F., Brix, S. (2017). The maternal microbiome during pregnancy and allergic disease in the offspring. Seminars in Immunopathology, 39(6), 669-675. [More Information]
• McKenzie, C., Tan, J., Macia, L., Mackay, C. (2017). The nutrition-gut microbiome-physiology axis and allergic diseases. Immunological Reviews, 278(1), 277-295. [More Information]

2016

• Chevalier, N., Tan, J., Mason, L., Robert, R., McKenzie, C., Lim, F., Wong, C., Macia, L., Thorburn, A., Russ, B., et al (2016). Avenues to autoimmune arthritis triggered by diverse remote inflammatory challenges. Journal of Autoimmunity, 73, 120-129. [More Information]
• Tan, J., McKenzie, C., Vuillermin, P., Goverse, G., Vinuesa, C., Mebius, R., Macia, L., Mackay, C. (2016). Dietary fiber and bacterial SCFA enhance oral tolerance and protect against food allergy through diverse cellular pathways. Cell Reports, 15(12), 2809-2824. [More Information]
• Lassen, K., McKenzie, C., Mari, M., Murano, T., Begun, J., Baxt, L., Goel, G., Villablanca, E., Kuo, S., Macia, L., et al (2016). Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk. Immunity, 44(6), 1392-1405. [More Information]
• Chevalier, N., Macia, L., Tan, J., Mason, L., Robert, R., Thorburn, A., Wong, C., Tsai, L., Bourne, K., Brink, R., et al (2016). The role of T follicular helper cell molecules, and environmental influences, for autoantibody production and progression to inflammatory arthritis in Mice. Arthritis & Rheumatology, 68(4), 1026-1038. [More Information]

2015

• Vieira, A., Macia, L., Galvao, I., Martins, F., Canesso, M., Amaral, F., Garcia, C., Maslowski, K., De Leon, E., Shim, D., et al (2015). A Role for Gut Microbiota and the Metabolite-Sensing Receptor GPR43 in a Murine Model of Gout. Arthritis & Rheumatology, 67(6), 1646-1656. [More Information]
• Thorburn, A., McKenzie, C., Shen, S., Stanley, D., Macia, L., Mason, L., Roberts, L., Wong, C., Shim, R., Robert, R., Mackay, C., et al (2015). Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites. Nature Communications, 6, 1-13. [More Information]
• McKenzie, C., Mackay, C., Macia, L. (2015). GPR43 - A Prototypic Metabolite Sensor Linking Metabolic and Inflammatory Diseases. Trends in Endocrinology and Metabolism, 26(10), 511-512. [More Information]
• Macia, L., Tan, J., Vieira, A., Leach, K., Stanley, D., Luong, S., Maruya, M., Ian McKenzie, C., Hijikata, A., et al (2015). Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome. Nature Communications, 6, 6734. [More Information]
• Wang-Wei Tsai, V., Macia, L., Feinle-Bisset, C., Manandhar, R., Astrup, A., Raben, A., Lorenzen, J., Schmidt, P., Wiklund, F., Pedersen, N., Salis (nee Sainsbury), A., et al (2015). Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI. PloS One, 10(7), 1-15. [More Information]
• Julia, V., Macia, L., Dombrowicz, D. (2015). The impact of diet on asthma and allergic diseases. Nature Reviews. Immunology, 15(5), 308-322. [More Information]

2014

• Thorburn, A., Macia, L., Mackay, C. (2014). Diet, metabolites, and "western-lifestyle" inflammatory diseases. Immunity, 40(6), 833-42. [More Information]
• Nguyen, A., Slack, K., Schwarzer, C., Lee, N., Boey, D., Macia, L., Yulyaningsih, E., Enriquez, R., Zhang, L., Lin, S., Salis (nee Sainsbury), A., et al (2014). Double deletion of orexigenic neuropeptide Y and dynorphin results in paradoxical obesity in mice. Neuropeptides, 48(3), 143-151. [More Information]
• Chevalier, N., Thorburn, A., Macia, L., Tan, J., Juglair, L., Yagita, H., Yu, D., Hansbro, P., Mackay, C. (2014). Inflammation and Lymphopenia Trigger Autoimmunity by Suppression of IL-2-Controlled Regulatory T Cell and Increase of IL-21-Mediated Effector T Cell Expansion. Journal of Immunology, 193(10), 4845-5488. [More Information]
• Yulyaningsih, E., Loh, K., Lin, S., Lau, J., Zhang, L., Shi, Y., Berning, B., Enriquez, R., Driessler, F., Macia, L., Salis (nee Sainsbury), A., et al (2014). Pancreatic polypeptide controls energy homeostasis via Npy6r signaling in the suprachiasmatic nucleus in mice. Cell Metabolism, 19(1), 58-72. [More Information]
• Tan, J., McKenzie, C., Potamitis, M., Thorburn, A., Mackay, C., Macia, L. (2014). The role of short-chain fatty acids in health and disease. Advances in Immunology, 121, 91-119. [More Information]

2013

• Tsai, V., Macia, L., Johnen, H., Kuffner, T., Manadhar, R., Jorgensen, S., Lee-Ng, K., Zhang, H., Wu, L., Marquis, C., Salis (nee Sainsbury), A., et al (2013). TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator. PloS One, 8(2), 1-10. [More Information]

2012

• Lucas, S., Taront, S., Magnan, C., Fauconnier, L., Delacre, M., Macia, L., Verwaerde, C., Spriet, C., Saule, P., Goormachtigh, G., et al (2012). Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms. PloS One, 7(6), e40351-0. [More Information]
• Macie, L., Tsai, V., Nguyen, A., Johnen, H., Kuffner, T., Shi, Y., Lin, S., Herzog, H., Brown, D., Breit, S., Salis (nee Sainsbury), A. (2012). Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets. PloS One, 7(4), 1-8. [More Information]
• Macia, L., Thorburn, A., Binge, L., Marino, E., Rogers, K., Maslowski, K., Vieira, A., Kranich, J., Mackay, C. (2012). Microbial influences on epithelial integrity and immune function as a basis for inflammatory diseases. Immunological Reviews, 245(1), 164-176. [More Information]
• Macia, L., Yulyaningsih, E., Pangon, L., Nguyen, A., Lin, S., Shi, Y., Zhang, L., Bijker, M., Grey, S., Mackay, F., Salis (nee Sainsbury), A., et al (2012). Neuropeptide Y1 Receptor in Immune Cells Regulates Inflammation and Insulin Resistance Associated With Diet-Induced Obesity. Diabetes, 61(12), 3228-3238. [More Information]
• Nguyen, A., Mitchell, N., Lin, S., Macia, L., Yulyaningsih, E., Baldock, P., Enriquez, R., Zhang, L., Shi, Y., Zolotukhin, S., Salis (nee Sainsbury), A., et al (2012). Y1 and Y5 Receptors are Both Required for the Regulation of Food Intake and Energy Homeostasis in Mice. PloS One, 7(6), 1-16. [More Information]

2011

• Shi, Y., Lin, S., Castillo, L., Aljanova, A., Enriquez, R., Nguyen, A., Baldock, P., Zhang, L., Bijker, M., Macia, L., Salis (nee Sainsbury), A., et al (2011). Peripheral-Specific Y2 Receptor Knockdown Protects Mice From High-Fat Diet-Induced Obesity. Obesity, 19(11), 2137-7148. [More Information]
• Macia, L., Rao, P., Wheway, J., Sierro, F., Mackay, F., Herzog, H. (2011). Y1 signalling has a critical role in allergic airway inflammation. Immunology and Cell Biology, 89(8), 882-888. [More Information]

2010

• Shi, Y., Lin, S., Wong, I., Baldock, P., Aljanova, A., Enriquez, R., Castillo, L., Mitchell, N., Ye, J., Zhang, L., Salis (nee Sainsbury), A., et al (2010). NPY Neuron-Specific Y2 Receptors Regulate Adipose Tissue and Trabecular Bone but Not Cortical Bone Homeostasis in Mice. PloS One, 5(6), 1-16. [More Information]

2009

• Lin, S., Shi, Y., Yulyaningsih, E., Aljanova, A., Zhang, L., Macia, L., Nguyen, A., Lin, E., During, M., Herzog, H., Salis (nee Sainsbury), A. (2009). Critical role of arcuate y4 receptors and the melanocortin system in pancreatic polypeptide-induced reduction in food intake in mice. PloS One, 4(12), e8488-e8488. [More Information]