People_

Associate Professor Muh Geot Wong

Associate Professor
Concord Clinical School
Faculty of Medicine and Health

Phone

+61 2 9926 4773

Fax

+61 2 9926 5715

Email

muhgeot.wong@sydney.edu.au

Resume

Curriculum vitae

Biographical details

Since I was awarded my PhD in 2011, I have worked as a part time clinician researcher at the Kolling Institute and at the George Institute. My main area of research is in understanding the pathomechanisms of kidney tubulointerstitial fibrosis, strategy in delaying CKD progression, and biomarkers in predicting progressive kidney disease especially in diabetic kidney disease and IgA nephropathy.I am the current Head of the Renal Clinical trial unit at the Royal North Shore Hospital (RNSH), and an active member of the a member of the Kolling Research Executive Committee for the Northern Sydney Lower Health District, which oversees the strategic development and operational effectiveness of the Clinical based research across the Area Health. I am part of the CARI guideline write-up group for Screening for infections in haemodialysis, and a member of the Scientific Program and Education Committee (SPEC) for the Australian New Zealand Society of Nephrology since 2015. I received several Young Investigator Awards and Early Career Awards at national and regional level in the past few years including the Young Investigator Awards at the Asia Pacific Congress of Nephrology, Tokyo in 2014.I successfully co-supervised two Master students and currently co-supervising two PhD students.

Research interests

My area of interest is inkidney tubulointerstitial fibrosis, strategy in delaying CKD progression, biomarkers reserach for CKD, randomised controlled clinical trials, and translational research.

Teaching and supervision

I supervise, train and examine medical students, basic physician trainees and advanced renal trainee at the Northern Clinical School. During the three years tenure as the Director of Physician Training of the Royal North Shore Hospital, forty five basic physician trainees were successful in the written and clinical Fellowship examination, with more than 95% of these trainees securing further specialty training positions. I successfully co-supervised two Master students and currently co-supervising two PhD students. Within my capacity as the Head of Renal Clinical Trial Unit, I lead a team of three Clinical Research Coordinators , and manage the daily operation, budget and contract negotiation of several clinical trials.

Themes

Obesity, Diabetes and Cardiovascular Disease, Reproductive, Maternal and Child Health, Lifespan

Keywords

Maternal health

Current research students

Project title	Research student
Risk prediction and mitigation in chronic kidney disease	Dana KIM

Publications

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Journals

Francis, A., Neuen, B., See, E., Shah, A., Smyth, B., Tungsanga, S., Viecelli, A., Yeung, E., Arruebo, S., Bello, A., Wong, M., Chen, T., et al (2024). Capacity for the management of kidney failure in the International Society of Nephrology Oceania and South East Asia (OSEA) region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA). Kidney International Supplements, 13(1), 110-122. [More Information]
Trachtman, H., Trimarchi, H., Wong, M., Mercer, A., Inrig, J., Rote, W., Murphy, E., Bedard, P., Roth, S., Bieler, S., et al (2024). Focal Segmental Glomerulosclerosis Patient Baseline Characteristics in the Sparsentan Phase 3 DUPLEX Study. Kidney International Reports. [More Information]
Cheung, C., Zhang, H., Perkovic, V., Rizk, D., Barratt, J., Carroll, K., Lafayette, R., Liew, A., Suzuki, Y., Tesar, V., Wong, M., et al (2024). Targeting APRIL in the Treatment of IgA Nephropathy. Clinical Journal of the American Society of Nephrology, 19(3), 394-398. [More Information]
Chung, E., Badve, S., Heerspink, H., Wong, M. (2023). Endothelin receptor antagonists in kidney protection for diabetic kidney disease and beyond? Nephrology, 28(2), 97-108. [More Information]
Barratt, J., Rovin, B., Wong, M., Alpers, C., Bieler, S., He, P., Inrig, J., Komers, R., Heerspink, H., Mercer, A., et al (2023). IgA Nephropathy Patient Baseline Characteristics in the Sparsentan PROTECT Study. Kidney International Reports, 8(5), 1043-1056. [More Information]
Campbell, K., Griffin, S., Trachtman, H., Geletka, R., Wong, M. (2023). Practical Considerations for the Use of Sparsentan in the Treatment of Patients with IgAN in Clinical Practice. International Journal of Nephrology and Renovascular Disease, 16, 281-291. [More Information]
Yugavathy, N., Abdullah, B., Lim, S., Abdul Gafor, A., Wong, M., Bavanandan, S., Wong, H., Huri, H. (2023). Precision Medicine in Erythropoietin Deficiency and Treatment Resistance: A Novel Approach to Management of Anaemia in Chronic Kidney Disease. Current Issues in Molecular Biology (Print), 45(8), 6550-6563. [More Information]
Macdougall, I., Meadowcroft, A., Blackorby, A., Cizman, B., Cobitz, A., Godoy, S., Jha, V., Johansen, K., McMahon, G., Obrador, G., et al (2023). Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D). American Journal of Nephrology, 54(1-2), 1-13. [More Information]
Pham, J., Sivasubramaniam, V., Gallagher, R., Forstner, D., Wong, M., Liu, J. (2023). Safety of cemiplimab for advanced cutaneous squamous cell carcinoma in a patient with p-ANCA-associated vasculitis. Journal of the European Academy of Dermatology and Venereology, 37(3), e363-e365. [More Information]
Heerspink, H., Radhakrishnan, J., Alpers, C., Barratt, J., Bieler, S., Diva, U., Inrig, J., Komers, R., Mercer, A., Noronha, I., Wong, M., et al (2023). Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial. The Lancet, 401(10388), 1584-1594. [More Information]
Rheault, M., Alpers, C., Barratt, J., Bieler, S., Canetta, P., Chae, D., Coppock, G., Diva, U., Gesualdo, L., Heerspink, H., et al (2023). Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis. New England Journal of Medicine, 389(26), 2436-2445. [More Information]
Zhang, J., Wong, M., Wong, M., Gross, S., Chen, J., Pollock, C., Saad, S. (2022). Correction: A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-β1. PloS One, 17(1), e0262725. [More Information]
Lv, J., Wong, M., Hladunewich, M., Jha, V., Hooi, L., Monaghan, H., Zhao, M., Barbour, S., Jardine, M., Reich, H., et al (2022). Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial. JAMA, 327(19), 1888-1898. [More Information]
Habibalahi, A., Campbell, J., Mahbub, S., Anwer, A., Nguyen, L., Gill, A., Wong, M., Chou, A., Pollock, C., Saad, S., et al (2022). moRphology - dEep Learning Imaging Cells (RELIC) - to Differentiate Between Normal and Pathological Kidney Exfoliated Cells. bioRxiv. [More Information]
Khor, C., Wong, M., Reagh, J. (2021). Anti-glomerular basement membrane disease and IgA nephropathy in a patient with previous renal cell carcinoma. BMJ Case Reports, 14(7). [More Information]
Oshima, M., Hara, A., Toyama, T., Jun, M., Pollock, C., Jardine, M., Harrap, S., Poulter, N., Cooper, M., Woodward, M., et al (2021). Comparison of Circulating Biomarkers in Predicting Diabetic Kidney Disease Progression With Autoantibodies to Erythropoietin Receptor. Kidney International Reports, 6(2), 284-295. [More Information]
Tiong, M., Krishnasamy, R., Smith, E., Hutchison, C., Ryan, E., Pascoe, E., Hawley, C., Hewitson, T., Jardine, M., Roberts, M., et al (2021). Effect of a medium cut-off dialyzer on protein-bound uremic toxins and mineral metabolism markers in patients on hemodialysis. Hemodialysis International, 25(3), 322-332. [More Information]
Ethier, I., Johnson, D., Bello, A., Ye, F., Osman, M., Levin, A., Harris, D., Kerr, P., Liew, A., Wong, M., et al (2021). International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in Oceania and South East Asia. Kidney International Supplements, 11(2), e86-e96. [More Information]
Ethier, I., Johnson, D., Bello, A., Ye, F., Osman, M., Levin, A., Harris, D., Kerr, P., Liew, A., Wong, M., et al (2021). International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in South Asia. Kidney International Supplements, 11(2), e97-e105. [More Information]
O'Hara, D., Wong, J., Cooper, B., Wong, G., Wong, M., Cheikh Hassan, H. (2021). Lessons for the clinical nephrologist: ureteric obstruction secondary to blood clot after kidney biopsy. Journal of Nephrology, 34(6), 2131-2136. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., et al (2021). Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1), 10655. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., Pollock, C., Saad, S. (2021). Publisher Correction: Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1). [More Information]
Wong, M., Lv, J., Hladunewich, M., Jha, V., Hooi, L., Monaghan, H., Zhao, M., Barbour, S., Reich, H., Cattran, D., Jardine, M., et al (2021). The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Study: Trial Design and Baseline Characteristics. American Journal of Nephrology, 52(10-Nov), 827-836. [More Information]
Krishnasamy, R., Hawley, C., Jardine, M., Roberts, M., Cho, Y., Wong, M., Heath, A., Nelson, C., Sen, S., Mount, P., et al (2020). A trial evaluating mid cut-off value membrane clearance of albumin and light chains in hemodialysis patients: A safety device study. Blood Purification, 49(4), 468-478. [More Information]
Liew, A., Bavanandan, S., Prasad, N., Wong, M., Chang, J., Eiam-Ong, S., Hao, C., Lim, C., Lim, S., Kook-Hwan, O., et al (2020). ASIAN PACIFIC SOCIETY OF NEPHROLOGY CLINICAL PRACTICE GUIDELINE ON DIABETIC KIDNEY DISEASE. Nephrology, 25, 12-45. [More Information]
Liew, A., Bavanandan, S., Prasad, N., Wong, M., Chang, J., Eiam-Ong, S., Hao, C., Lim, C., Lim, S., Kook-Hwan, O., et al (2020). ASIAN PACIFIC SOCIETY OF NEPHROLOGY CLINICAL PRACTICE GUIDELINE ON DIABETIC KIDNEY DISEASE - EXECUTIVE SUMMARY. Nephrology, 25, 3-11. [More Information]
Liew, A., Bavanandan, S., Prasad, N., Wong, M., Chang, J., Eiam-Ong, S., Hao, C., Lim, C., Lim, S., Kook-Hwan, O., et al (2020). Asian Pacific Society of Nephrology Clinical Practice Guideline on Diabetic Kidney Disease – An Executive Summary. Nephrology, 25(11), 809-817. [More Information]
Cherney, D., Dekkers, C., Barbour, S., Cattran, D., Abdul Gafor, A., Greasley, P., Laverman, G., Lim, S., Di Tanna, G., Reich, H., et al (2020). Effects of the SGLT2 inhibitor dapagliflozin on proteinuria in non-diabetic patients with chronic kidney disease (DIAMOND): a randomised, double-blind, crossover trial. The Lancet Diabetes and Endocrinology, 8(7), 582-593. [More Information]
Hultin, S., Nahar, K., Menzies, A., Long, G., Fernando, S., Atkinson, V., Cebon, J., Wong, M. (2020). Histological diagnosis of immune checkpoint inhibitor induced acute renal injury in patients with metastatic melanoma: A retrospective case series report. BMC Nephrology, 21(1), 391. [More Information]
Chatterton, S., Williams, S., Nahar, K., Menzies, A., Wong, M. (2020). Immunotherapy-related acute kidney injury: Kidney biopsy or not? Nephrology, 26(1), 89-90. [More Information]
Wong, M., Saad, S., Wong, M., Stangenberg, S., Jarolimek, W., Schilter, H., Zaky, A., Gill, A., Pollock, C. (2020). Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy. PloS One, 15(6), e0234617. [More Information]
Leaver, P., Jang, H., Wong, M., Soh, H., Fernando, S. (2019). ANCA-associated vasculitis of the appendix. Rheumatology Advances in Practice, 3(2), 1-3. [More Information]
Toyama, T., Neuen, B., Jun, M., Ohkuma, T., Neal, B., Jardine, M., Heerspink, H., Wong, M., Ninomiya, T., Wada, T., et al (2019). Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: A systematic review and meta-analysis. Diabetes, Obesity and Metabolism, 21(5), 1237-1250. [More Information]
Jardine, M., Commons, R., de Zoysa, J., Wong, M., Gilroy, N., Green, J., Henderson, B., Stuart, R., Tunnicliffe, D., van Eps, C., et al (2019). Kidney Health Australia - Caring for Australasians with Renal Impairment guideline recommendations for infection control for haemodialysis units. Nephrology, 24(9), 951-957. [More Information]
Wong, M., Ninomiya, T., Liyanage, T., Sukkar, L., Hirakawa, Y., Wang, Y., Wyld, M., Morton, R., Chadban, S., Howard, K., et al (2019). Physical component Quality of life (QOL) reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 QOL: an AUSDiab analysis. Nephrology, 24(6), 605-614. [More Information]
Nguyen, L., Mak, C., Chen, H., Zaky, A., Wong, M., Pollock, C., Saad, S. (2019). SIRT1 Attenuates Kidney Disorders in Male Offspring Due to Maternal High-Fat Diet. Nutrients, 11(1), 1-14. [More Information]
Wyld, M., Morton, R., Clayton, P., Wong, M., Jardine, M., Polkinghorne, K., Chadban, S. (2019). The impact of progressive chronic kidney disease on health-related quality-of-life: a 12-year community cohort study. Quality of Life Research, 28(8), 2081-2090. [More Information]
Wong, M., Heerspink, H., Perkovic, V. (2018). ACCORDION: Ensuring That We Hear the Music Clearly. Clinical Journal of the American Society of Nephrology, 13(11), 1621-1623. [More Information]
Krishnasamy, R., Hawley, C., Jardine, M., Roberts, M., Cho, Y., Wong, M., Heath, A., Nelson, C., Sen, S., Mount, P., et al (2018). Design and methods of the REMOVAL-HD study: a tRial Evaluating Mid cut-Off Value membrane clearance of Albumin and Light chains in HaemoDialysis patients. BMC Nephrology, 19(1), 89. [More Information]
Radholm, K., Wu, J., Wong, M., Foote, C., Fulcher, G., Mahaffey, K., Perkovic, V., Neal, B. (2018). Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular disease, death and safety outcomes in type 2 diabetes - A systematic review. Diabetes Research and Clinical Practice, 140, 118-128. [More Information]
Wong, M., Jardine, M., Perkovic, V. (2018). Glucose lowering and the kidney: are all drug classes equal? The Lancet Diabetes & Endocrinology, 6(11), 835-837. [More Information]
Wong, M., The, N., Glastras, S. (2018). Maternal obesity and offspring risk of chronic kidney disease. Nephrology, 23(Suppl 4), 84-87. [More Information]
Lv, J., Zhang, H., Wong, M., Jardine, M., Hladunewich, M., Jha, V., Monaghan, H., Zhao, M., Barbour, S., Reich, H., Perkovic, V., et al (2017). Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial. JAMA, 318(5), 432-442. [More Information]
Miller, H., Jaure, A., Tunnicliffe, D., Campbell, D., Pinter, J., Commons, R., Athan, E., Craig, J., Gilroy, N., Green, J., Howell, M., Wong, M., Jardine, M., et al (2017). Identifying and integrating patient and caregiver perspectives for clinical practice guidelines on the screening and management of infectious microorganisms in hemodialysis units. Hemodialysis International, 21(2), 213-223. [More Information]
Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17. [More Information]
Gallagher, M., Wong, M., Perkovic, V. (2016). ALTITUDE: defining a ceiling for blockade of the renin-angiotensin system? The Lancet Diabetes and Endocrinology, 4(4), 289-290. [More Information]
Sukkar, L., Hong, D., Wong, M., Badve, S., Rogers, K., Perkovic, V., Walsh, M., Yu, X., Hillis, G., Gallagher, M., Jardine, M. (2016). Effects of ischaemic conditioning on major clinical outcomes in people undergoing invasive procedures: systematic review and meta-analysis. BMJ, 355, 1-10. [More Information]
Liyanage, T., Ninomiya, T., Wang, A., Neal, B., Jun, M., Wong, M., Jardine, M., Hillis, G., Perkovic, V. (2016). Effects of the mediterranean diet on cardiovascular outcomes-a systematic review and meta-analysis. PloS One, 11(8), 1-11. [More Information]
Wong, M., Perkovic, V. (2016). Knowing what we do not know: statin therapy in advanced chronic kidney disease. The Lancet Diabetes & Endocrinology, 4(10), 801-803. [More Information]
Wong, M., Perkovic, V., Chalmers, J., Woodward, M., Li, Q., Cooper, M., Hamet, P., Harrap, S., Heller, S., MacMahon, S., Neal, B., Rodgers, A., Zoungas, S., et al (2016). Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON. Diabetes Care, 39(5), 694-700. [More Information]
Glastras, S., Chen, H., Teh, R., McGrath, R., Chen, J., Pollock, C., Wong, M., Saad, S. (2016). Mouse models of diabetes, obesity and related kidney disease. PloS One, 11(8), 1-15. [More Information]
Stangenberg, S., Chen, H., Wong, M., Pollock, C., Saad, S. (2015). Fetal programming of chronic kidney disease: The role of maternal smoking, mitochondrial dysfunction, and epigenetic modfification. American Journal of Physiology: Renal Physiology, 308(11), F1189-F1196. [More Information]
Glastras, S., Wong, M., Chen, H., Zhang, J., Zaky, A., Pollock, C., Saad, S. (2015). FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity. Nutrition and Metabolism, 12(1), 1-13. [More Information]
Wong, M., Wanner, C., Knight, J., Perkovic, V. (2015). Lowering cholesterol in chronic kidney disease: is it safe and effective? European Heart Journal, 36(43), 2988-2995. [More Information]
Wong, M., Pollock, C., Cooper, B., Branley, P., Collins, J., Craig, J., Kesselhut, J., Luxton, G., Pilmore, A., Harris, D., et al (2014). Association between GFR Estimated by Multiple Methods at Dialysis Commencement and Patient Survival. Clinical Journal of the American Society of Nephrology, 9(1), 135-142. [More Information]
Wong, M., Pollock, C. (2014). Biomarkers in kidney fibrosis: Are they useful? Kidney International Supplements, 4(1), 79-83. [More Information]
Knight, J., Wong, M., Perkovic, V. (2014). Optimal targets for blood pressure control in chronic kidney disease: the debate continues. Current Opinion In Nephrology And Hypertension, 23(6), 541-546. [More Information]
Wong, M., Saad, S., Zhang, J., Gross, S., Jarolimek, W., Schilter, H., Chen, J., Gill, A., Pollock, C., Wong, M. (2014). Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model. AJP: Renal Physiology (Online), 307(8), F908-F916. [More Information]
Al-Odat, I., Chen, H., Chan, Y., Amgad, S., Wong, M., Gill, A., Pollock, C., Saad, S. (2014). The Impact of Maternal Cigarette Smoke Exposure in a Rodent Model on Renal Development in the Offspring. PloS One, 9(7), 1-10. [More Information]
Wong, M., Perkovic, V., Woodward, M., Chalmers, J., Li, Q., Hillis, G., Azari, E., Jun, M., Poulter, N., Hamet, P., Neal, B., Pollock, C., et al (2013). Circulating bone morphogenetic protein-7 and transforming growth factor-(beta)1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney International, 83(2), 278-284. [More Information]
Saad, S., Zhang, J., Yong, R., Yaghobian, D., Wong, M., Kelly, D., Chen, X., Pollock, C. (2013). Role of the EGF receptor in PPARgamma-mediated sodium and water transport in human proximal tubule cells. Diabetologia, 56(5), 1174-1182. [More Information]
Wong, M., Saad, S., Pollock, C., Wong, M. (2013). Semicarbazide-sensitive amine oxidase and kidney disease. American Journal of Physiology: Renal Physiology, 305(12), F1637-F1644. [More Information]
Johnson, D., Wong, M., Cooper, B., Branley, P., Bulfone, L., Collins, J., Craig, J., Fraenkel, M., Harris, A., Kesselhut, J., Tiller, D., Harris, D., Pollock, C., et al (2012). Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial. Peritoneal Dialysis International, 32(6), 595-604. [More Information]
Wong, M., Panchapakesan, U., Qi, W., Silva, D., Chen, X., Pollock, C. (2011). Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-B1. American Journal of Physiology: Renal Physiology, 301(1), F84-F93. [More Information]
Amarasekara, C., Uppal, T., Wong, M. (2011). Post partum flare in a patient with hereditary angioedema. Sri Lanka Journal of Obstetrics and Gynaecology, 33(4), 166-167.
McGregor, A., Ogwu, C., Uppal, T., Wong, M. (2011). Spontaneous subcutaneous emphysema and pneumomediastinum during second stage of labour. BMJ Case Reports. [More Information]
Wong, M., Suzuki, Y., Tanifuji, C., Akiba, H., Okumura, K., Sugaya, T., Yamamoto, T., Horikoshi, S., Tan, S., Pollock, C., et al (2008). Peritubular Ischemia Contributes More to Tubular Damage than Proteinuria in Immune-Mediated Glomerulonephritis. Journal of the American Society of Nephrology, 19(2), 290-297. [More Information]

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By Year

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2024

Francis, A., Neuen, B., See, E., Shah, A., Smyth, B., Tungsanga, S., Viecelli, A., Yeung, E., Arruebo, S., Bello, A., Wong, M., Chen, T., et al (2024). Capacity for the management of kidney failure in the International Society of Nephrology Oceania and South East Asia (OSEA) region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA). Kidney International Supplements, 13(1), 110-122. [More Information]
Trachtman, H., Trimarchi, H., Wong, M., Mercer, A., Inrig, J., Rote, W., Murphy, E., Bedard, P., Roth, S., Bieler, S., et al (2024). Focal Segmental Glomerulosclerosis Patient Baseline Characteristics in the Sparsentan Phase 3 DUPLEX Study. Kidney International Reports. [More Information]
Cheung, C., Zhang, H., Perkovic, V., Rizk, D., Barratt, J., Carroll, K., Lafayette, R., Liew, A., Suzuki, Y., Tesar, V., Wong, M., et al (2024). Targeting APRIL in the Treatment of IgA Nephropathy. Clinical Journal of the American Society of Nephrology, 19(3), 394-398. [More Information]

2023

Chung, E., Badve, S., Heerspink, H., Wong, M. (2023). Endothelin receptor antagonists in kidney protection for diabetic kidney disease and beyond? Nephrology, 28(2), 97-108. [More Information]
Barratt, J., Rovin, B., Wong, M., Alpers, C., Bieler, S., He, P., Inrig, J., Komers, R., Heerspink, H., Mercer, A., et al (2023). IgA Nephropathy Patient Baseline Characteristics in the Sparsentan PROTECT Study. Kidney International Reports, 8(5), 1043-1056. [More Information]
Campbell, K., Griffin, S., Trachtman, H., Geletka, R., Wong, M. (2023). Practical Considerations for the Use of Sparsentan in the Treatment of Patients with IgAN in Clinical Practice. International Journal of Nephrology and Renovascular Disease, 16, 281-291. [More Information]
Yugavathy, N., Abdullah, B., Lim, S., Abdul Gafor, A., Wong, M., Bavanandan, S., Wong, H., Huri, H. (2023). Precision Medicine in Erythropoietin Deficiency and Treatment Resistance: A Novel Approach to Management of Anaemia in Chronic Kidney Disease. Current Issues in Molecular Biology (Print), 45(8), 6550-6563. [More Information]
Macdougall, I., Meadowcroft, A., Blackorby, A., Cizman, B., Cobitz, A., Godoy, S., Jha, V., Johansen, K., McMahon, G., Obrador, G., et al (2023). Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D). American Journal of Nephrology, 54(1-2), 1-13. [More Information]
Pham, J., Sivasubramaniam, V., Gallagher, R., Forstner, D., Wong, M., Liu, J. (2023). Safety of cemiplimab for advanced cutaneous squamous cell carcinoma in a patient with p-ANCA-associated vasculitis. Journal of the European Academy of Dermatology and Venereology, 37(3), e363-e365. [More Information]
Heerspink, H., Radhakrishnan, J., Alpers, C., Barratt, J., Bieler, S., Diva, U., Inrig, J., Komers, R., Mercer, A., Noronha, I., Wong, M., et al (2023). Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial. The Lancet, 401(10388), 1584-1594. [More Information]
Rheault, M., Alpers, C., Barratt, J., Bieler, S., Canetta, P., Chae, D., Coppock, G., Diva, U., Gesualdo, L., Heerspink, H., et al (2023). Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis. New England Journal of Medicine, 389(26), 2436-2445. [More Information]

show 5 more

2022

Zhang, J., Wong, M., Wong, M., Gross, S., Chen, J., Pollock, C., Saad, S. (2022). Correction: A Cationic-Independent Mannose 6-Phosphate Receptor Inhibitor (PXS64) Ameliorates Kidney Fibrosis by Inhibiting Activation of Transforming Growth Factor-β1. PloS One, 17(1), e0262725. [More Information]
Lv, J., Wong, M., Hladunewich, M., Jha, V., Hooi, L., Monaghan, H., Zhao, M., Barbour, S., Jardine, M., Reich, H., et al (2022). Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial. JAMA, 327(19), 1888-1898. [More Information]
Habibalahi, A., Campbell, J., Mahbub, S., Anwer, A., Nguyen, L., Gill, A., Wong, M., Chou, A., Pollock, C., Saad, S., et al (2022). moRphology - dEep Learning Imaging Cells (RELIC) - to Differentiate Between Normal and Pathological Kidney Exfoliated Cells. bioRxiv. [More Information]

2021

Khor, C., Wong, M., Reagh, J. (2021). Anti-glomerular basement membrane disease and IgA nephropathy in a patient with previous renal cell carcinoma. BMJ Case Reports, 14(7). [More Information]
Oshima, M., Hara, A., Toyama, T., Jun, M., Pollock, C., Jardine, M., Harrap, S., Poulter, N., Cooper, M., Woodward, M., et al (2021). Comparison of Circulating Biomarkers in Predicting Diabetic Kidney Disease Progression With Autoantibodies to Erythropoietin Receptor. Kidney International Reports, 6(2), 284-295. [More Information]
Tiong, M., Krishnasamy, R., Smith, E., Hutchison, C., Ryan, E., Pascoe, E., Hawley, C., Hewitson, T., Jardine, M., Roberts, M., et al (2021). Effect of a medium cut-off dialyzer on protein-bound uremic toxins and mineral metabolism markers in patients on hemodialysis. Hemodialysis International, 25(3), 322-332. [More Information]
Ethier, I., Johnson, D., Bello, A., Ye, F., Osman, M., Levin, A., Harris, D., Kerr, P., Liew, A., Wong, M., et al (2021). International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in Oceania and South East Asia. Kidney International Supplements, 11(2), e86-e96. [More Information]
Ethier, I., Johnson, D., Bello, A., Ye, F., Osman, M., Levin, A., Harris, D., Kerr, P., Liew, A., Wong, M., et al (2021). International Society of Nephrology Global Kidney Health Atlas: structures, organization, and services for the management of kidney failure in South Asia. Kidney International Supplements, 11(2), e97-e105. [More Information]
O'Hara, D., Wong, J., Cooper, B., Wong, G., Wong, M., Cheikh Hassan, H. (2021). Lessons for the clinical nephrologist: ureteric obstruction secondary to blood clot after kidney biopsy. Journal of Nephrology, 34(6), 2131-2136. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., et al (2021). Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1), 10655. [More Information]
Mahbub, S., Nguyen, L., Habibalahi, A., Campbell, J., Anwer, A., Qadri, U., Gill, A., Chou, A., Wong, M., Gosnell, M., Pollock, C., Saad, S. (2021). Publisher Correction: Non-invasive assessment of exfoliated kidney cells extracted from urine using multispectral autofluorescence features. Scientific Reports, 11(1). [More Information]
Wong, M., Lv, J., Hladunewich, M., Jha, V., Hooi, L., Monaghan, H., Zhao, M., Barbour, S., Reich, H., Cattran, D., Jardine, M., et al (2021). The Therapeutic Evaluation of Steroids in IgA Nephropathy Global (TESTING) Study: Trial Design and Baseline Characteristics. American Journal of Nephrology, 52(10-Nov), 827-836. [More Information]

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2020

Krishnasamy, R., Hawley, C., Jardine, M., Roberts, M., Cho, Y., Wong, M., Heath, A., Nelson, C., Sen, S., Mount, P., et al (2020). A trial evaluating mid cut-off value membrane clearance of albumin and light chains in hemodialysis patients: A safety device study. Blood Purification, 49(4), 468-478. [More Information]
Liew, A., Bavanandan, S., Prasad, N., Wong, M., Chang, J., Eiam-Ong, S., Hao, C., Lim, C., Lim, S., Kook-Hwan, O., et al (2020). ASIAN PACIFIC SOCIETY OF NEPHROLOGY CLINICAL PRACTICE GUIDELINE ON DIABETIC KIDNEY DISEASE. Nephrology, 25, 12-45. [More Information]
Liew, A., Bavanandan, S., Prasad, N., Wong, M., Chang, J., Eiam-Ong, S., Hao, C., Lim, C., Lim, S., Kook-Hwan, O., et al (2020). ASIAN PACIFIC SOCIETY OF NEPHROLOGY CLINICAL PRACTICE GUIDELINE ON DIABETIC KIDNEY DISEASE - EXECUTIVE SUMMARY. Nephrology, 25, 3-11. [More Information]
Liew, A., Bavanandan, S., Prasad, N., Wong, M., Chang, J., Eiam-Ong, S., Hao, C., Lim, C., Lim, S., Kook-Hwan, O., et al (2020). Asian Pacific Society of Nephrology Clinical Practice Guideline on Diabetic Kidney Disease – An Executive Summary. Nephrology, 25(11), 809-817. [More Information]
Cherney, D., Dekkers, C., Barbour, S., Cattran, D., Abdul Gafor, A., Greasley, P., Laverman, G., Lim, S., Di Tanna, G., Reich, H., et al (2020). Effects of the SGLT2 inhibitor dapagliflozin on proteinuria in non-diabetic patients with chronic kidney disease (DIAMOND): a randomised, double-blind, crossover trial. The Lancet Diabetes and Endocrinology, 8(7), 582-593. [More Information]
Hultin, S., Nahar, K., Menzies, A., Long, G., Fernando, S., Atkinson, V., Cebon, J., Wong, M. (2020). Histological diagnosis of immune checkpoint inhibitor induced acute renal injury in patients with metastatic melanoma: A retrospective case series report. BMC Nephrology, 21(1), 391. [More Information]
Chatterton, S., Williams, S., Nahar, K., Menzies, A., Wong, M. (2020). Immunotherapy-related acute kidney injury: Kidney biopsy or not? Nephrology, 26(1), 89-90. [More Information]
Wong, M., Saad, S., Wong, M., Stangenberg, S., Jarolimek, W., Schilter, H., Zaky, A., Gill, A., Pollock, C. (2020). Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy. PloS One, 15(6), e0234617. [More Information]

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2019

Leaver, P., Jang, H., Wong, M., Soh, H., Fernando, S. (2019). ANCA-associated vasculitis of the appendix. Rheumatology Advances in Practice, 3(2), 1-3. [More Information]
Toyama, T., Neuen, B., Jun, M., Ohkuma, T., Neal, B., Jardine, M., Heerspink, H., Wong, M., Ninomiya, T., Wada, T., et al (2019). Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: A systematic review and meta-analysis. Diabetes, Obesity and Metabolism, 21(5), 1237-1250. [More Information]
Jardine, M., Commons, R., de Zoysa, J., Wong, M., Gilroy, N., Green, J., Henderson, B., Stuart, R., Tunnicliffe, D., van Eps, C., et al (2019). Kidney Health Australia - Caring for Australasians with Renal Impairment guideline recommendations for infection control for haemodialysis units. Nephrology, 24(9), 951-957. [More Information]
Wong, M., Ninomiya, T., Liyanage, T., Sukkar, L., Hirakawa, Y., Wang, Y., Wyld, M., Morton, R., Chadban, S., Howard, K., et al (2019). Physical component Quality of life (QOL) reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 QOL: an AUSDiab analysis. Nephrology, 24(6), 605-614. [More Information]
Nguyen, L., Mak, C., Chen, H., Zaky, A., Wong, M., Pollock, C., Saad, S. (2019). SIRT1 Attenuates Kidney Disorders in Male Offspring Due to Maternal High-Fat Diet. Nutrients, 11(1), 1-14. [More Information]
Wyld, M., Morton, R., Clayton, P., Wong, M., Jardine, M., Polkinghorne, K., Chadban, S. (2019). The impact of progressive chronic kidney disease on health-related quality-of-life: a 12-year community cohort study. Quality of Life Research, 28(8), 2081-2090. [More Information]

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2018

Wong, M., Heerspink, H., Perkovic, V. (2018). ACCORDION: Ensuring That We Hear the Music Clearly. Clinical Journal of the American Society of Nephrology, 13(11), 1621-1623. [More Information]
Krishnasamy, R., Hawley, C., Jardine, M., Roberts, M., Cho, Y., Wong, M., Heath, A., Nelson, C., Sen, S., Mount, P., et al (2018). Design and methods of the REMOVAL-HD study: a tRial Evaluating Mid cut-Off Value membrane clearance of Albumin and Light chains in HaemoDialysis patients. BMC Nephrology, 19(1), 89. [More Information]
Radholm, K., Wu, J., Wong, M., Foote, C., Fulcher, G., Mahaffey, K., Perkovic, V., Neal, B. (2018). Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular disease, death and safety outcomes in type 2 diabetes - A systematic review. Diabetes Research and Clinical Practice, 140, 118-128. [More Information]
Wong, M., Jardine, M., Perkovic, V. (2018). Glucose lowering and the kidney: are all drug classes equal? The Lancet Diabetes & Endocrinology, 6(11), 835-837. [More Information]
Wong, M., The, N., Glastras, S. (2018). Maternal obesity and offspring risk of chronic kidney disease. Nephrology, 23(Suppl 4), 84-87. [More Information]

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2017

Lv, J., Zhang, H., Wong, M., Jardine, M., Hladunewich, M., Jha, V., Monaghan, H., Zhao, M., Barbour, S., Reich, H., Perkovic, V., et al (2017). Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial. JAMA, 318(5), 432-442. [More Information]
Miller, H., Jaure, A., Tunnicliffe, D., Campbell, D., Pinter, J., Commons, R., Athan, E., Craig, J., Gilroy, N., Green, J., Howell, M., Wong, M., Jardine, M., et al (2017). Identifying and integrating patient and caregiver perspectives for clinical practice guidelines on the screening and management of infectious microorganisms in hemodialysis units. Hemodialysis International, 21(2), 213-223. [More Information]
Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17. [More Information]

2016

Gallagher, M., Wong, M., Perkovic, V. (2016). ALTITUDE: defining a ceiling for blockade of the renin-angiotensin system? The Lancet Diabetes and Endocrinology, 4(4), 289-290. [More Information]
Sukkar, L., Hong, D., Wong, M., Badve, S., Rogers, K., Perkovic, V., Walsh, M., Yu, X., Hillis, G., Gallagher, M., Jardine, M. (2016). Effects of ischaemic conditioning on major clinical outcomes in people undergoing invasive procedures: systematic review and meta-analysis. BMJ, 355, 1-10. [More Information]
Liyanage, T., Ninomiya, T., Wang, A., Neal, B., Jun, M., Wong, M., Jardine, M., Hillis, G., Perkovic, V. (2016). Effects of the mediterranean diet on cardiovascular outcomes-a systematic review and meta-analysis. PloS One, 11(8), 1-11. [More Information]
Wong, M., Perkovic, V. (2016). Knowing what we do not know: statin therapy in advanced chronic kidney disease. The Lancet Diabetes & Endocrinology, 4(10), 801-803. [More Information]
Wong, M., Perkovic, V., Chalmers, J., Woodward, M., Li, Q., Cooper, M., Hamet, P., Harrap, S., Heller, S., MacMahon, S., Neal, B., Rodgers, A., Zoungas, S., et al (2016). Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON. Diabetes Care, 39(5), 694-700. [More Information]
Glastras, S., Chen, H., Teh, R., McGrath, R., Chen, J., Pollock, C., Wong, M., Saad, S. (2016). Mouse models of diabetes, obesity and related kidney disease. PloS One, 11(8), 1-15. [More Information]

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2015

Stangenberg, S., Chen, H., Wong, M., Pollock, C., Saad, S. (2015). Fetal programming of chronic kidney disease: The role of maternal smoking, mitochondrial dysfunction, and epigenetic modfification. American Journal of Physiology: Renal Physiology, 308(11), F1189-F1196. [More Information]
Glastras, S., Wong, M., Chen, H., Zhang, J., Zaky, A., Pollock, C., Saad, S. (2015). FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity. Nutrition and Metabolism, 12(1), 1-13. [More Information]
Wong, M., Wanner, C., Knight, J., Perkovic, V. (2015). Lowering cholesterol in chronic kidney disease: is it safe and effective? European Heart Journal, 36(43), 2988-2995. [More Information]

2014

Wong, M., Pollock, C., Cooper, B., Branley, P., Collins, J., Craig, J., Kesselhut, J., Luxton, G., Pilmore, A., Harris, D., et al (2014). Association between GFR Estimated by Multiple Methods at Dialysis Commencement and Patient Survival. Clinical Journal of the American Society of Nephrology, 9(1), 135-142. [More Information]
Wong, M., Pollock, C. (2014). Biomarkers in kidney fibrosis: Are they useful? Kidney International Supplements, 4(1), 79-83. [More Information]
Knight, J., Wong, M., Perkovic, V. (2014). Optimal targets for blood pressure control in chronic kidney disease: the debate continues. Current Opinion In Nephrology And Hypertension, 23(6), 541-546. [More Information]
Wong, M., Saad, S., Zhang, J., Gross, S., Jarolimek, W., Schilter, H., Chen, J., Gill, A., Pollock, C., Wong, M. (2014). Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model. AJP: Renal Physiology (Online), 307(8), F908-F916. [More Information]
Al-Odat, I., Chen, H., Chan, Y., Amgad, S., Wong, M., Gill, A., Pollock, C., Saad, S. (2014). The Impact of Maternal Cigarette Smoke Exposure in a Rodent Model on Renal Development in the Offspring. PloS One, 9(7), 1-10. [More Information]

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2013

Wong, M., Perkovic, V., Woodward, M., Chalmers, J., Li, Q., Hillis, G., Azari, E., Jun, M., Poulter, N., Hamet, P., Neal, B., Pollock, C., et al (2013). Circulating bone morphogenetic protein-7 and transforming growth factor-(beta)1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney International, 83(2), 278-284. [More Information]
Saad, S., Zhang, J., Yong, R., Yaghobian, D., Wong, M., Kelly, D., Chen, X., Pollock, C. (2013). Role of the EGF receptor in PPARgamma-mediated sodium and water transport in human proximal tubule cells. Diabetologia, 56(5), 1174-1182. [More Information]
Wong, M., Saad, S., Pollock, C., Wong, M. (2013). Semicarbazide-sensitive amine oxidase and kidney disease. American Journal of Physiology: Renal Physiology, 305(12), F1637-F1644. [More Information]

2012

Johnson, D., Wong, M., Cooper, B., Branley, P., Bulfone, L., Collins, J., Craig, J., Fraenkel, M., Harris, A., Kesselhut, J., Tiller, D., Harris, D., Pollock, C., et al (2012). Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the ideal trial. Peritoneal Dialysis International, 32(6), 595-604. [More Information]

2011

Wong, M., Panchapakesan, U., Qi, W., Silva, D., Chen, X., Pollock, C. (2011). Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-B1. American Journal of Physiology: Renal Physiology, 301(1), F84-F93. [More Information]
Amarasekara, C., Uppal, T., Wong, M. (2011). Post partum flare in a patient with hereditary angioedema. Sri Lanka Journal of Obstetrics and Gynaecology, 33(4), 166-167.
McGregor, A., Ogwu, C., Uppal, T., Wong, M. (2011). Spontaneous subcutaneous emphysema and pneumomediastinum during second stage of labour. BMJ Case Reports. [More Information]

2008

Wong, M., Suzuki, Y., Tanifuji, C., Akiba, H., Okumura, K., Sugaya, T., Yamamoto, T., Horikoshi, S., Tan, S., Pollock, C., et al (2008). Peritubular Ischemia Contributes More to Tubular Damage than Proteinuria in Immune-Mediated Glomerulonephritis. Journal of the American Society of Nephrology, 19(2), 290-297. [More Information]

Selected Grants

2023

Associate Professor in Medicine (Nephrology) Support Package, Wong M, Faculty of Medicine and Health/Startup funds support

2017

A novel diagnostic method to determine the likelihood of kidney fibrosis and progressive CKD in patients with diabetes mellitus and other forms of chronic proteinuric renal disease, Pollock C, Saad S, Goldys E, Fulcher G, Wong M, National Health and Medical Research Council (NHMRC)/Project Grants

2015

Do circulating transforming growth factor-Î²1 and bone morphogenetic protein-7 predict progression of CKD in patients with type 2 diabetes mellitus, Wong M, Clive and Vera Ramaciotti Foundations/Awards for Biomedical Research: Establishment Gifts

2014

The role of three novel agents in limiting kidney fibrosis in a model of diabetic nephropathy, Wong M, Royal Australasian College of Physicians/Jacquot Research Establishment Award

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