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Machine learning of -omic data for discovery of disease processes.

This project builds on a number of recent findings and aims to bring together omics data related to disease and machine learning for the prediction of transcriptional regulators inv more...

Supervisor(s): Waardenberg, Ashley (Dr), Arthur , Jonathan (Associate Professor)

Pathways to therapies in blinding genetic retinal eye diseases

In this project, novel disease genes and variants are identified that cause blinding retinal eye diseases. Cellular, gene editing, proteomic and animal model approaches are taken to more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

Genomic medicine for unravelling the challenges of pathogenesis and treatment of blindness due to childhood cataract and glaucoma

Novel disease genes and variants are identified that contribute to the blinding eye diseases of childhood cataract and glaucoma.  In this project further novel variants will be more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

Pharmacological targeting of the metastasis suppressor NDRG1 using novel therapeutics

Metastasis is the major killer in cancer, being extremely difficult to treat. This project will elucidate the molecular mechanisms that initiate and sustain metastatic progression, more...

Supervisor(s): Kovacevic, Zaklina (Dr), Richardson, Des (Professor)

Investigation on the causes for keratoconus

This project will be suitable for PhD students, and it can also be broken down to small projects for master students. It is basic science research based, and the student will experi more...

Supervisor(s): Sutton, Gerard (Professor), You, Jingjing (Dr)

Genetic diversity of commercial black tiger prawns and evidence for selection signatures (University of Sydney & James Cook University)

This project will use genotype-by-sequencing approaches to determine differences in genetic diversity between populations of farmed black tiger prawns (Penaeus monodon) originating more...

Supervisor(s): Khatkar, Mehar Singh (Dr), Thomson, Peter Campbell (Associate Professor)

Genotype by environment interactions under commercial scenarios on performance of black tiger prawn genotypes (University of Sydney & James Cook University)

This project aims to understand the influence of genotype by environment (GxE) interactions on realizing the genetic potential of the black tiger prawn to guide the design of both t more...

Supervisor(s): Thomson, Peter Campbell (Associate Professor), Khatkar, Mehar Singh (Dr)

Pathogen-host interactions and resilience on-farm.

This project forms part of an integrated new program on resilience to endemic disease. The project aims to (i) investigate host-pathogen interactions and pathogen evolution for an i more...

Supervisor(s): Plain, Karren (Dr)

Mining genomic data to understand diseases

In this project, we aim to develop, apply ,and enhance bioinformatics and statistical tools to effectively collate, query, and mine public data repositories of transcription factor more...

Supervisor(s): Khushi, Matloob (Dr)

Novel therapy to prevent and treat kidney fibrosis

Progressive kidney disease is a global health burden most commonly caused by diabetes and obesity, which are dramatically on the rise. In Australia, 1 in 3 adults are at risk of dev more...

Supervisor(s): Saad, Sonia (Dr), Pollock, Carol (Professor)