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Investigating novel molecular mechanisms in motor neuron disease.

This project will use molecular and cell biology approaches to investigate known and novel motor neuron disease genes and the functional consequences of disease causing mutations. more...

Supervisor(s): Nicholson, Garth (Professor)

Preventing rejection of transplanted organs without using immunosuppressive drugs

The project aims to identify molecular pathways to prevent rejection of transplanted organs in animal models and to apply these findings to clinical transplantation. more...

Supervisor(s): Bishop, Alex (Dr)

Drug Discovery and Medicinal Chemistry for the Central Nervous System

Projects involve developing novel CNS drugs through applications of organic synthesis, medicinal chemistry and pharmacological screening. more...

Supervisor(s): Kassiou, Michael (Professor)

Glucocorticoid effects on bone: The role of the osteoblast

 Glucocorticoid effects on bone: The role of the osteoblast more...

Supervisor(s): Seibel, Markus (Professor), Zhou, Hong (Professor)

Regulating prosclerosing growth factors by incretin therapy in diabetic cardiomyopathy

Growth factors induced by diabetes contribute to tissue fibrosis and dysfunction, in conditions such as diabetic cardiomyopathy, and there is preliminary evidence that the incretins more...

Supervisor(s): Twigg, Stephen (Professor)

Strategies for Building Bone

This project will investigate the use of biological agents in stimulating bone growth and inhibiting bone resorption. more...

Supervisor(s): Zreiqat, Hala (Professor)

Surface modification of biomaterials for orthopaedic applications

This project will establish that our novel modified calcium silicate materials have enhanced bioactivity and osseointegration properties for coatings onto orthopaedic implants. more...

Supervisor(s): Zreiqat, Hala (Professor)

Scaffolds for skeletal tissue regeneration

This project will modify calcium silicate ceramic scaffolds with divalent cations to improve their mechanical, osteoinductive and osteoconductive properties for bone regeneration. more...

Supervisor(s): Zreiqat, Hala (Professor)

Role of S100A8 and S100A9 in osteoarthritis

This projects involves the development of novel scaffolds and biomaterials for bone and cartilage regeneration. more...

Supervisor(s): Zreiqat, Hala (Professor)