Application of new DNA sequencing and genotyping technologies in animal health and improvement

Summary

Multiple doctoral research opportunities exist to explore the use of new DNA sequencing technologies to advance our understanding of the genomic biology.

Supervisor(s)

Professor Claire Wade

Research Location

Sydney School of Veterinary Science

Program Type

Masters/PHD

Synopsis

Technology is constantly advancing and offering greater capacity for understanding the complexity of animal genomic biology. Maximising the application of this technology to advance animal genetic health and welfare is a common goal. We will explore the use of 3rd generation DNA sequencing technologies to advance our understanding of the genomic biology. For example, to explore the inheritance patterns of duplicated regions of the mammalian genome across generations and to understand the role of segmental duplications in animal health and performance.New DNA sequencing and genotyping technologies will be applied to improve our understanding of mammalian genome biology. Depending on the interests of the student, we will apply the latest genomic analysis methods to study applications of new genomic technologies to improve the effectiveness and affordability of genotyping by sequencing or gene mapping in animal populations and to better understand the relationship between DNA and phenotype.We are looking for Doctor of Philosophy candidates with a passionate interest in animal genomics. The ideal student will be willing to undertake a predominantly computational project. Occasional opportunities for laboratory work and animal handling are available within the projects.Our laboratory is particularly interested in Companion Animal genetic and genomic research but other species will be considered. Illumina HiSeq 2000 light whole genomic survey sequence data is available for dog breeds represented by multiple individuals. We also have access to cat and horse data. We aim to begin using 3rd generation DNA sequencing in 2015.No stipend or student fee funding is available for this project at this time but overseas students with available funding are welcome to apply. Domestic students with Honours class 1 in a natural science or computing field that are eligible for Australian Postgraduate Awards are encouraged.

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Keywords

Comparative genomics, DNA, Sequencing, Next-generation, Bioinformatics, programming

Opportunity ID

The opportunity ID for this research opportunity is: 1877