The adaptive and innate immune systems of crocodilians

Summary

This project focuses on characterising and investigating the evolution and diversity of the adaptive and innate systems and their association with diseases in crocodilians, with a focus in particular on saltwater and freshwater crocodiles. 

Supervisor(s)

Associate Professor Jaime Gongora

Research Location

Sydney School of Veterinary Science

Program Type

Masters/PHD

Synopsis

This project will focus on the diversity of the major histocompatibility complex and complement system to identify the rearrangements and gain and/or loss of genes. Also within the scope of the project is MHC diversity among populations of saltwater and freshwater crocodiles and disease association studies of relevance to the crocodile industry. This project will involve analyses of genome sequence and RNA-Seq data and use of deep amplicon sequencing, DNA capture and traditional molecular genetic approaches.  

Additional Information

HDR Inherent Requirements

In addition to the academic requirements set out in the Science Postgraduate Handbook, you may be required to satisfy a number of inherent requirements to complete this degree. Example of inherent requirement may include:

- Confidential disclosure and registration of a disability that may hinder your performance in your degree;
- Confidential disclosure of a pre-existing or current medical condition that may hinder your performance in your degree (e.g. heart disease, pace-maker, significant immune suppression, diabetes, vertigo, etc.);
- Ability to perform independently and/or with minimal supervision;
- Ability to undertake certain physical tasks (e.g. heavy lifting);
- Ability to undertake observatory, sensory and communication tasks;
- Ability to spend time at remote sites (e.g. One Tree Island, Narrabri and Camden);
- Ability to work in confined spaces or at heights;
- Ability to operate heavy machinery (e.g. farming equipment);
- Hold or acquire an Australian driver’s licence;
- Hold a current scuba diving license;
- Hold a current Working with Children Check;
- Meet initial and ongoing immunisation requirements (e.g. Q-Fever, Vaccinia virus, Hepatitis, etc.)

You must consult with your nominated supervisor regarding any identified inherent requirements before completing your application.

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Keywords

innate immune systems crocodilians RNA-Seq data DNA saltwater and freshwater crocodiles

Opportunity ID

The opportunity ID for this research opportunity is: 2107

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