Refining cell-based therapies to cure diabetes

Summary

The most promising route for a cure for type 1 diabetes is the use of insulin-secreting cells to replace those that have died.

Supervisor(s)

Professor Peter Thorn

Research Location

Charles Perkins Centre – the Judith and David Coffey Life Lab

Program Type

Masters/PHD

Synopsis

This project will use human pluripotent stem cells and use techniques to grow insulin-secreting cells. Work in other labs has followed this method but the cells secrete little insulin and do not respond properly to glucose. The PhD student will build on the experience and data from our lab that shows how beta cells behave in native islets and aim to recapitulate this by refining the conditions of cell culture. The PhD student will work with other members of the lab in Sydney and collaborate with stem cell labs in Queensland.

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Keywords

islet, diabetes, insulin, Imaging, Stem cells

Opportunity ID

The opportunity ID for this research opportunity is: 786