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Genomic medicine for unravelling the challenges of pathogenesis and treatment of blindness due to childhood cataract and glaucoma

Novel disease genes and variants are identified that contribute to the blinding eye diseases of childhood cataract and glaucoma.  In this project further novel variants will be more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

Investigating the role of a novel RNA binding protein in telomerase activity

We have identified a role for a novel RNA binding protein in telomerase biogenesis and recruitment to telomeres. We aim to investigate how this protein functions in this context usi more...

Supervisor(s): Pickett, Hilda (Associate Professor)

Gene function and RNA processing in gut endoderm development

This project aims to unravel the impact of RNA processing on the function the targets of a RNA binding protein in the development of the embryonic gut and the associated organs. more...

Supervisor(s): Fossat, Nicolas (Dr), Tam, Patrick (Professor)

Machine learning of -omic data for discovery of disease processes.

This project builds on a number of recent findings and aims to bring together omics data related to disease and machine learning for the prediction of transcriptional regulators inv more...

Supervisor(s): Waardenberg, Ashley (Dr), Arthur , Jonathan (Associate Professor)

Image processing for understanding cell biology

In this project we aim to develop novel image and video processing algorithms and pipelines to better understand cell biology. more...

Supervisor(s): Khushi, Matloob (Dr)

The DNA replication stress response

Genome integrity in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)

Pathways to therapies in blinding genetic retinal eye diseases

In this project, novel disease genes and variants are identified that cause blinding retinal eye diseases. Cellular, gene editing, proteomic and animal model approaches are taken to more...

Supervisor(s): Jamieson, Robyn (Associate Professor)

Gene therapy for genetic and acquired diseases of the liver and haematopoietic system.

We are working on developing new therapies for the treatment of genetic and acquired diseases of the liver and haematopoietic system. The Gene Therapy Research Unit has a diverse se more...

Supervisor(s): Alexander, Ian (Professor), Ginn, Samantha (Dr), Logan, Grant (Dr)

How do molecules make memories? Understanding synaptic plasticity at the level of protein pathways and signalling.

This project aims to discover and validate new molecular mechanisms of how synaptic plasticity, which underlies learning and memory, is regulated by protein interactions and phospho more...

Supervisor(s): Graham, Mark (Dr)