Your Search Results

Biochemistry and cell biology of the cancer-associated enzyme telomerase

Telomerase is the enzyme responsible for lengthening the ends of chromosomes (telomeres), thereby allowing most cancer cells to divide indefinitely.  We are determining the mec more...

Supervisor(s): Bryan, Tracy (Associate Professor), Cohen, Scott (Dr)

Control of cell differentiation during mouse embryogenesis and stem cell development

The research will provide insights into how progenitor cells for embryonic tissues may be specified and determine the conditions that promote differentiation into germ layer derivat more...

Supervisor(s): Tam, Patrick (Professor)

The uncharted molecular mechanisms of nerve cell communication

Advances in proteomics technology have allowed a more detailed understanding of the proteins and signalling that regulate neurotransmitter release. This project will delve deeper in more...

Supervisor(s): Graham, Mark (Dr)

Head Development: Intersection of transcriptional and signalling activities

This project is designed to test the hypothesis that head formation during embryogenesis is controlled by a multitude of interacting transcriptional and signalling activities and t more...

Supervisor(s): Tam, Patrick (Professor), Fossat, Nicolas (Dr)

Telomere deprotection and cancer

Genome stability in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)

Mining genomic data to understand diseases

In this project, we aim to develop, apply ,and enhance bioinformatics and statistical tools to effectively collate, query, and mine public data repositories of transcription factor more...

Supervisor(s): Khushi, Matloob (Dr)

Development of efficient algorithms to manipulate genomic regions

The aim of this project is to develop novel and efficient database algorithms to process genomic data. more...

Supervisor(s): Khushi, Matloob (Dr)

Computational prediction of treatment outcome by machine learning

In this project we will implement and develop novel machine learning techniques to predict a best treatment plan for a patient. more...

Supervisor(s): Khushi, Matloob (Dr)

The regulation of neurotransmitter release by active zone proteins

This project will aim to discover and validate new molecular mechanisms of how neurotransmitter release and synaptic plasticity is regulated by active zone protein interactions and more...

Supervisor(s): Graham, Mark (Dr)

Pathways to therapies in blinding genetic retinal eye diseases

In this project, novel disease genes and variants are identified that cause blinding retinal eye diseases. Cellular, gene editing, proteomic and animal model approaches are taken to more...

Supervisor(s): Jamieson, Robyn (Associate Professor)