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Design of new metal-based anti-cancer drugs

This project aims to investigate the mode of action of metal anti-cancer drugs, including both anti-metastatic and cytotocities against a range of different cancer cell lines.  more...

Supervisor(s): Lay, Peter (Professor)

Targeted delivery of anticancer agents

An ideal anticancer agent is one that is inert as it moves around the body, is selectively taken up by cancer cells, and is activated once inside those cells. The multiple oxidation more...

Supervisor(s): Hambley, Trevor (Emeritus Professor)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of Novel Anti-Cancer Agents

Are you interested in applying your laboratory expertise to the development of new drugs for cancer and other diseases?  Become part of a multi-disciplinary team involved in dr more...

Supervisor(s): Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

Gadolinium complexes as new theranostic agents for brain cancer

The 5-year survival rate for patients afflicted with aggressive and intractable brain tumours (gliomas) is less than 4%.  In this project, we will incorporate Gd3+ ions into mi more...

Supervisor(s): Rendina, Louis (Professor)

Investigating the links between telomerase and the DNA damage response in cancer cells

The ribonucleoprotein enzyme telomerase counteracts telomere shortening in a majority of cancers, allowing for unlimited cell division. Most normal cells do not express telomerase, more...

Supervisor(s): Bryan, Tracy (Professor)

A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)

THE USE OF MARIJUANA AND/OR ENDOCANNABINOID OILS FOR THE TREATMENT OF OSTEOARTHRITIS (OA)

Pre-clinical studies for the effects of CBD and analogues for the treatment of osteoarthritis more...

Supervisor(s): Manolios, Nicholas (Professor), Arnold, Jonathon (Associate Professor)

GENES AND CELL-CELL INTERACTIONS IN CANCER PROGRESSION..

Oncogenes, tumour suppressor genes and cell-cell interactions in cancer: which are important in driving tumour progression and invasion in squamous cell carcinomas? more...

Supervisor(s): Lyons, Guy (Associate Professor)

Medicinal Chemistry and Biology - Development of Novel Anti-Tumour Agents for Cancer Treatment

This project is involved in the exciting development of novel drugs for the treatment of cancer and other conditions. more...

Supervisor(s): Richardson, Des (Professor)