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Medicinal Chemistry and Biology - Development of Novel Anti-Tumour Agents for Cancer Treatment

This project is involved in the exciting development of novel drugs for the treatment of cancer and other conditions. more...

Supervisor(s): Richardson, Des (Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

How do gingipains recognise their host cell targets?

Porphyromonas gingivalis is a gram-negative, rod-shaped anaerobic pathogenic bacterium that found in the oral cavity. more...

Supervisor(s): Collyer, Charles (Associate Professor)

Novel inhalation formulation to improve quality of life of cystic fibrosis sufferers

Respiratory infection is the number one cause of death world-wide with limited therapies other than tablet or intravenous injection. This multi-faceted PhD project will focus on dev more...

Supervisor(s): Traini, Daniela (Professor)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Role of Vitamin D and other compounds in protection of skin cells from UV

This study examines how vitamin D compounds protect skin from sun or UV-induced DNA and other damage. more...

Supervisor(s): Mason, Rebecca (Professor)

Determining the functional significance of non-coding DNA variants in genes for complex traits involving gene-environmental interactions

To identify non-protein coding DNA changes in genes that interact with the environment using 2 models – sporadic amyotrophic lateral sclerosis for the vulnerability to environ more...

Supervisor(s): Yu, Bing (Associate Professor)

Engineering human tissue

You will engineer tissue repair constructs from extracellular matrix using elastin, which is an essential component of the skin and artery. more...

Supervisor(s): Weiss, Tony (Professor)

Bioactive Lipid Modulation of Glycine Transporters and Glycine Receptors

A major focus of our work is on the design, synthesis and development of new bioactive lipids that inhibit glycine transporters. These compounds represent a new class of allosteric more...

Supervisor(s): Vandenberg, Robert (Professor)

Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)