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Dysregulation of the inflammatory response in diabetes: Its role in poor wound healing

Diabetes is known to alter inflammatroy response but how this contributes to poor wound healing and other complications of diabetes is not known and will be investigated in this wor more...

Supervisor(s): McLennan, Susan (Dr), Shackel, Nicholas (Dr), Min, Danqing (Dr)

Early signs of diabetes complications in childhood onset diabetes mellitus

Early signs of diabetes complications in childhood onset diabetes will focus on newer methods to assess heart rate variation, peripheral nerve function, colour vision and vascular c more...

Supervisor(s): Donaghue, Kim (Professor)

Towards a cure for Type I diabetes mellitus

Retroviral expression of an immunosuppressive peptide in the prevention of islet cell transplantation. more...

Supervisor(s): Manolios, Nicholas (Professor)

Regulating prosclerosing growth factors by incretin therapy in diabetic cardiomyopathy

Growth factors induced by diabetes contribute to tissue fibrosis and dysfunction, in conditions such as diabetic cardiomyopathy, and there is preliminary evidence that the incretins more...

Supervisor(s): Twigg, Stephen (Professor)

Understanding ageing of the endothelium

The investigations are focussed on identifying the biological and molecular changes that occur when endothelial cells undergo senescence (ageing) and the impact on disease such as d more...

Supervisor(s): Gamble, Jennifer (Professor)

Impact of hyperglycaemia on hospitalised patients

We are looking at the relationship between hyperglycaemia and adverse hospital outcome in a variety of clinical situations. more...

Supervisor(s): Cheung, Ngai Wah (Associate Professor)

Biology of Dipeptidyl Peptidase IV and related proteins

Research projects centre on mouse models of liver disease and obesity and on the delineation of inhibitors, substrates, biochemistry and in vivo expression and function of the Dipep more...

Supervisor(s): Gorrell, Mark (Associate Professor)

Prostate cancer metabolism – investigating the role of lipid metabolism and the microenvironment

This project aims to investigate potential interaction the different cell types near the prostate gland and how changes in androgen signalling alters this relationship. It also aims more...

Supervisor(s): Hoy, Andrew (Dr)

Interplay between Innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection

This study is to investigate the link between innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection with a view to identifying new therapeutic t more...

Supervisor(s): Chadban, Steve (Professor), Wu, Huiling (Associate Professor)

Chronic kidney disease in the developing world

This project will examine chronic kidney disease (CKD) from a global perspective. With collaboration with our research partners in Sri Lanka at the South Asian Clinical Toxicology R more...

Supervisor(s): Osborne, Nicholas (Dr)