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Determining the functional significance of non-coding DNA variants in genes for complex traits involving gene-environmental interactions

To identify non-protein coding DNA changes in genes that interact with the environment using 2 models – sporadic amyotrophic lateral sclerosis for the vulnerability to environ more...

Supervisor(s): Yu, Bing (Associate Professor)

Role of Vitamin D and other compounds in protection of skin cells from UV

This study examines how vitamin D compounds protect skin from sun or UV-induced DNA and other damage. more...

Supervisor(s): Mason, Rebecca (Professor)

Biochemistry and cell biology of the cancer-associated enzyme telomerase

Telomerase is the enzyme responsible for lengthening the ends of chromosomes (telomeres), thereby allowing most cancer cells to divide indefinitely.  We are determining the mec more...

Supervisor(s): Bryan, Tracy (Associate Professor), Cohen, Scott (Dr)

Dissemination of antibiotic resistance genes in commensal Escherichia coli

This project will examine the Escherichia coli present in the gut of healthy adults who have not been recently exposed to antibiotics to determine the prevalence of antibiotic resis more...

Supervisor(s): Hall, Ruth (Professor)

A weighty problem- how the protein TPD52 regulates cellular lipid storage

This project seeks to better understand why some cancer cells contain high levels of stored lipid, and whether this property can be targeted for cancer therapy. more...

Supervisor(s): Byrne, Jennifer (Professor), Chen, Yuyan (Dr)

Bioinformatics approach to Cryptosporidium identity: database prospects

The Bioinformatics approach to Cryptosporidium identity: database prospects study will examine (i) the applicability of web based platform to clinical and field data and (ii) develo more...

Supervisor(s): Slapeta, Jan (Professor)

Regulatory Proteins in Development and Disease

PhD projects in this laboratory are focused on understanding how key proteins can lead to both normal development and disease, and using this knowledge to develop reagents to inhibi more...

Supervisor(s): Matthews, Jacqueline (Professor)

Genetic control of resistance and susceptibility to tuberculosis

Both environmental and genetic factors influence susceptibility to tuberculosis; this project will identify and investigate polymorphisms in genes that may increase susceptibility t more...

Supervisor(s): Saunders, Bernadette (Dr)

Emerging parasitic disease: epidemiological, diagnostic and experimental approach

The project Emerging parasitic diseases: epidemiological, diagnostic and experimental approach will focus on development and elucidation of the epidemiology of newly or neglected di more...

Supervisor(s): Slapeta, Jan (Professor)

Concord Health and Ageing in Men Project (CHAMP)

CHAMP is a large epidemiological study of ageing in men, with a particular focus on Alzheimer’s disease, osteoporosis and urinary incontinence. more...

Supervisor(s): Cumming , Robert G (Professor)