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The cellular and molecular regulation of embryo development

Postgraduate research studentship in the molecular and cellular analysis of key embryonic transitions. The research program will investigate how changes in histone and DNA methylati more...

Supervisor(s): O'Neill, Chris (Professor)

The effect of assisted reproductive technologies on embryo development and postnatal health.

Postgraduate research studentship in the analysis of the effects of assisted reproductive technology on the normal development of the embryo. The host lab is a pioneer in the develo more...

Supervisor(s): O'Neill, Chris (Professor)

Regulation of Hematopoietic Stem Cell Production in the Embryo and Adult

In this project we will ask what regulates the appearance and production of hematopoietic stem cells during embryonic development in the mouse and whether these processes also take more...

Supervisor(s): Fraser, Stuart (Dr)

Embryonic stem cells

Embryonic stem (ES) cells have the potential to differentiate into any cell type of the developing embryo and adult. For this reason they have proved invaluable in understanding the more...

Supervisor(s): Morris, Michael (Dr)

Generation of a sheep model of Batten disease using the CRISPR/Cas9 genome editing system

The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are a group of fatal neurodegenerative inherited diseases in humans and animals (http://bdsra.org/). There is no cure, but more...

Supervisor(s): Tammen, Imke (Associate Professor), Grupen, Christopher Gerald (Associate Professor)

Red blood cell enucleation

Prior to entering the blood stream, developing erythroid or red blood cells condense and expel their nucleus. This unusual process occurs millions of times per minute in a healthy a more...

Supervisor(s): Fraser, Stuart (Dr)

Effect of cardioactive drugs on the developing rat heart

Cardioactive drugs are used during pregnancy to alleviate heart conditions but may affect the heart of the developing fetus. more...

Supervisor(s): Ritchie, Helen (Dr)

Control of cell differentiation during mouse embryogenesis and stem cell development

The research will provide insights into how progenitor cells for embryonic tissues may be specified and determine the conditions that promote differentiation into germ layer derivat more...

Supervisor(s): Tam, Patrick (Professor)

Gene function and RNA processing in gut endoderm development

This project aims to unravel the impact of RNA processing on the function the targets of a RNA binding protein in the development of the embryonic gut and the associated organs. more...

Supervisor(s): Fossat, Nicolas (Dr), Tam, Patrick (Professor)

Head Development: Intersection of transcriptional and signalling activities

This project is designed to test the hypothesis that head formation during embryogenesis is controlled by a multitude of interacting transcriptional and signalling activities and t more...

Supervisor(s): Tam, Patrick (Professor), Fossat, Nicolas (Dr)