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Effect of cardioactive drugs on the developing rat heart

Cardioactive drugs are used during pregnancy to alleviate heart conditions but may affect the heart of the developing fetus. more...

Supervisor(s): Ritchie, Helen (Dr)

Protein and peptide biomarkers of myocardial ischemia

This project will identify novel biomarkers (diagnostics) of ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

The role of calcium overload in myocardial ischemia / reperfusion injury

This project aims to identify the biochemical targets of calcium overload responsible for ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Investigation of the role of microRNAs in cell differentiation

Investigating the role of microRNAs in the regulation of stem cell multipotency and differentiation. more...

Supervisor(s): Rasko, John (Professor)

Inhertied and acquired platelet function defects

Bleeding defects in Australian patients and families will be characterised using genomic and proteomic analysis more...

Supervisor(s): Ward, Chris (Professor)

Investigating mechanisms of microparticle production by microvascular endothelial cells and defining clinically useful inhibitors

To study the role of microparticles in causing a major complication of malaria infection, namely cerebral malaria. more...

Supervisor(s): Grau, Georges (Professor)

Regulating prosclerosing growth factors by incretin therapy in diabetic cardiomyopathy

Growth factors induced by diabetes contribute to tissue fibrosis and dysfunction, in conditions such as diabetic cardiomyopathy, and there is preliminary evidence that the incretins more...

Supervisor(s): Twigg, Stephen (Professor)

Engineering human tissue

You will engineer tissue repair constructs from extracellular matrix using elastin, which is an essential component of the skin and artery. more...

Supervisor(s): Weiss, Tony (Professor)

Determining the functional significance of non-coding DNA variants in genes for complex traits involving gene-environmental interactions

To identify non-protein coding DNA changes in genes that interact with the environment using 2 models – sporadic amyotrophic lateral sclerosis for the vulnerability to environ more...

Supervisor(s): Yu, Bing (Associate Professor)

Developing small molecules that enhance PCSK9/AnxA2 interaction to inhibit PCSK9 and elevate LDLR levels

Statins to decrease low density lipoprotein cholesterol (LDL-C) are a cornerstone to prevent and treat cardiovascular events. However, inadequate dose response, resistance, and seri more...

Supervisor(s): Grewal , Thomas (Associate Professor)