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Imaging atherogenesis in a zebrafish model

This project will characterise immune cell dynamics during atherogenesis by live imaging, and investigate the importance of vascular remodelling and leakage in fuelling atheroma pat more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)

Understanding how cell polarity is patterned in plants

The symmetrical arrangements of leaves and flowers have long fascinated artists and mathematicians alike for hundreds of years. Using live-imaging, molecular biology and genetics, t more...

Supervisor(s): Heisler, Marcus (Associate Professor)

Unravelling mechanisms determining the balance between tolerance and immunity in the liver

Role of primary T cell activation in the liver in CD8 T cell tolerance more...

Supervisor(s): Bertolino, Patrick (Dr)

Investigating the role of a novel RNA binding protein in telomerase activity

We have identified a role for a novel RNA binding protein in telomerase biogenesis and recruitment to telomeres. We aim to investigate how this protein functions in this context usi more...

Supervisor(s): Pickett, Hilda (Associate Professor)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

Telomere deprotection and cancer

Genome stability in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)

Targeting melanoma secretory pathways.

Cancer cells secrete a variety of factors that induce tumour growth, metastasis, angiogenesis, and alter the tumour stroma to create a more favourable microenviroment. This project more...

Supervisor(s): Weninger , Wolfgang (Professor), Beaumont, Kimberley (Dr)

The DNA replication stress response

Genome integrity in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)

Neuroscience/Neuroimmunology Research: Role of antibody in brain immune-mediated diseases

The Institute of Neuromuscular Research (INMR) is part of the Children's Hospital at Westmead (CHW), the largest paediatric centre in NSW, providing the most advanced care and treat more...

Supervisor(s): Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

HUMAN MINIBRAINS GROWN FROM STEM CELLS

This project will involve CRISPR genome editing strategies combined with human stem cell derived mini-brains to investigate new neuronal factors that control development, cognitive more...

Supervisor(s): Neely, Greg (Associate Professor)