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Carboranes as unique boron frameworks in medicinal chemistry

Boron-based drugs are increasingly being investigated in many disease categories, with numerous pharmaceutical companies (e.g. GSK, Anacor, and Takeda) dramatically expanding their more...

Supervisor(s): Rendina, Louis (Professor)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of New Anti-Bacterial Agents

This project would appeal to those with interests in pharmaceutical applications of medicinal and protein chemistry. more...

Supervisor(s): Groundwater, Paul (Professor), Church, W Bret (Dr), Hibbs, David (Dai) (Professor)

Drug Discovery and Medicinal Chemistry for the Central Nervous System

Projects involve developing novel CNS drugs through applications of organic synthesis, medicinal chemistry and pharmacological screening. more...

Supervisor(s): Kassiou, Michael (Professor)

Organic and Supramolecular Chemistry

The synthesis of cyclic peptides and derivatives is currently of significant interest, due to their potential applications in a range of areas spanning both chemistry and biology. N more...

Supervisor(s): Jolliffe, Katrina (Kate) (Professor)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of Novel Anti-Cancer Agents

Are you interested in applying your laboratory expertise to the development of new drugs for cancer and other diseases?  Become part of a multi-disciplinary team involved in dr more...

Supervisor(s): Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

Medicinal Chemistry and Biology - Development of Novel Anti-Tumour Agents for Cancer Treatment

This project is involved in the exciting development of novel drugs for the treatment of cancer and other conditions. more...

Supervisor(s): Richardson, Des (Professor)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Associate Professor)

Gadolinium complexes as new theranostic agents for brain cancer

The 5-year survival rate for patients afflicted with aggressive and intractable brain tumours (gliomas) is less than 4%.  In this project, we will incorporate Gd3+ ions into mi more...

Supervisor(s): Rendina, Louis (Professor)

Bioactive Lipid Modulation of Glycine Transporters and Glycine Receptors

A major focus of our work is on the design, synthesis and development of new bioactive lipids that inhibit glycine transporters. These compounds represent a new class of allosteric more...

Supervisor(s): Vandenberg, Robert (Professor)

New epidermal growth factor receptor (EGFR) inhibitors for the treatment of cancer

Molecular modelling and synthesis and characterisation of the hit compounds, biological testing in cell based assays and the determination of the inhibition of receptor dimerisation more...

Supervisor(s): Hibbs, David (Dai) (Professor)