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Prostate cancer metabolism – investigating the role of lipid metabolism and the microenvironment

This project aims to investigate potential interaction the different cell types near the prostate gland and how changes in androgen signalling alters this relationship. It also aims more...

Supervisor(s): Hoy, Andrew (Dr)

Link between ATP supply and consumption in the maintenance of the shape of the red blood cell in normal and disease states

The link between the main energy supply (ATP from glycolysis) and its consumption by the cytoskeleton will be studied by using nuclear magnetic resonance (NMR) spectroscopy, compute more...

Supervisor(s): Kuchel, Philip (Emeritus Professor)

A weighty problem- how the protein TPD52 regulates cellular lipid storage

This project seeks to better understand why some cancer cells contain high levels of stored lipid, and whether this property can be targeted for cancer therapy. more...

Supervisor(s): Byrne, Jennifer (Professor), Chen, Yuyan (Dr)

Amino acid sensing mechanisms in human biology.

Amino acid sensing mechanisms determine how dietary protein regulates appetite and satiety, how feeding influences endocrine responses and how nutrition can direct cell fate in brea more...

Supervisor(s): Conigrave, Arthur (Professor)

Phosphate homeostasis and fungal virulence

Inorganic phosphate (Pi) is an important macronutrient for all living organisms including yeast, and is essential for ATP, phospholipid and protein synthesis, metabolism and signall more...

Supervisor(s): Djordjevic, Julianne (Dr), Sorrell, Tania (Professor)

Studies on tumour active compounds

New anticancer drugs and synergism from drug combinations. more...

Supervisor(s): Huq, Fazlul (Associate Professor)

Glucocorticoid effects on bone: The role of the osteoblast

 Glucocorticoid effects on bone: The role of the osteoblast more...

Supervisor(s): Seibel, Markus (Professor), Zhou, Hong (Professor)

Biology of Dipeptidyl Peptidase IV and related proteins

Research projects centre on mouse models of liver disease and obesity and on the delineation of inhibitors, substrates, biochemistry and in vivo expression and function of the Dipep more...

Supervisor(s): Gorrell, Mark (Associate Professor)

Kinetic Characterization and Mapping for Whole-body Molecular Image Retrieval

In vivo kinetic behaviour characterization and dynamic holistic mapping for efficient dual-modality whole-body molecular imaging data retrieval. more...

Supervisor(s): Feng, David (Professor), Cai, Tom Weidong (Associate Professor)