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Muscle specific kinase in synaptic adaptation

This project will investigate the role of postsynaptic Muscle specific Kinase (MuSK) in regulating presynaptic neurotransmitter release at the neuromuscular junction. more...

Supervisor(s): Phillips, William (Bill) (Associate Professor), Protti, Dario (Dr)

Mapping genes for nerve disease

Our laboratory has an exemplary track record for mapping genes for inherited peripheral neuropathies. Charcot-Marie-Tooth (CMT) neuropathy is a degenerative disorder of the peripher more...

Supervisor(s): Kennerson, Marina (Associate Professor), Nicholson, Garth (Professor)

A cell culture model for Muscle Specific Kinase myasthenia gravis

The postsynaptic membrane of the neuromuscular junction (NMJ) is organized by Muscle specific tyrosine kinase (MuSK). This project will investigate the mechanisms that organize the more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

Synaptic signalling therapies for anti-acetylcholine receptor myasthenia gravis

This project will use a mouse model to test potential treatments for the autoimmune disease, anti-acetylcholine receptor myasthenia gravis. more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

Dysferlin and defective membrane repair in muscular dystrophy

We are studying a form of muscular dystrophy caused by deficiency of the protein dysferlin. Dysferlin patients have a primary defect in skeletal muscle membrane repair, and are unab more...

Supervisor(s): Cooper, Sandra (Dr)

Prevention of athletic knee injuries

The aim of this project is to evaluate the effectiveness of knee injury prevention programs that are tailored to athletes' neuromuscular deficits. more...

Supervisor(s): Pappas, Evangelos (Associate Professor), Simic, Milena (Dr)

Predicting chronic ankle disability

This project consists of a series of studies to identify mechanisms of ongoing symptoms and disability after ankle injury, to design and test treatments to prevent ongoing symptoms, more...

Supervisor(s): Refshauge, Kathryn (Professor), Hiller, Claire (Dr)

Walk Again: Enabling Standing and Walking after Neurological Impairment

This project is a cluster of research studies investigating health benefits of Functional Electrical Stimulation (FES), neurorobotics and other "blue sky" assistive technologies for more...

Supervisor(s): Davis, Glen (Professor)

Strengthening brittle bones

Osteogenesis imperfecta (OI) or "brittle bone disease" can be caused by a range of proteins involved with the bone matrix. Children with OI are prone to fracture, which can reduce m more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor), Munns, Craig (Associate Professor)

Antibody-Mediated Pain Syndrome (AMPS)

Complex regional pain syndromes (CRPSs) are painful disorders with pathophysiological etiologies associated with neuroinflammation, peripheral nerve damage, central sensitization, more...

Supervisor(s): Parratt, John (Dr), Ng, Karl (Associate Professor)