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Investigating the links between telomerase and the DNA damage response in cancer cells

The ribonucleoprotein enzyme telomerase counteracts telomere shortening in a majority of cancers, allowing for unlimited cell division. Most normal cells do not express telomerase, more...

Supervisor(s): Bryan, Tracy (Professor)

Protein and peptide biomarkers of myocardial ischemia

This project will identify novel biomarkers (diagnostics) of ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Mitochondial DNA damage, potential target to reduce the development of renal disorders induced by maternal smoking .

Smoking rates are disproportionately high in disadvantaged populations, particularly in emerging economies, and increasing in women of child bearing age. more...

Supervisor(s): Saad, Sonia (Dr)

Assessing changes to myocardial proteins subsequent to experimental heart attack

Post translational changes to key cardiac proteins in the hearts of diabetic rats after experimental heart attack more...

Supervisor(s): Witting, Paul (Dr)

Prevention of cardiac side effects of cancer treatment

This project will investigate a novel drug combination therapy that has potential benefits in cancer treatment induced heart failure by targeting Na+-K+ pump function. more...

Supervisor(s): Liu, Chia-chi (Dr), Ramussen, Helge (Professor)

The role of calcium overload in myocardial ischemia / reperfusion injury

This project aims to identify the biochemical targets of calcium overload responsible for ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Engineering human tissue

You will engineer tissue repair constructs from extracellular matrix using elastin, which is an essential component of the skin and artery. more...

Supervisor(s): Weiss, Tony (Professor)

Inhertied and acquired platelet function defects

Bleeding defects in Australian patients and families will be characterised using genomic and proteomic analysis more...

Supervisor(s): Ward, Chris (Professor)

A New Therapeutic Strategy to Overcome Multidrug Resistance by Exploiting Drug-Transporters to Target Untreatable Cancers

We recently have discovered a frontier strategy for overcoming drug resistance mediated by P-glycoprotein (Pgp) in the lysosome. Identifying new targets for resistant cancers are cr more...

Supervisor(s): Jansson, Patric (Dr)

The autonomic consequences of sleep apnoea: A critical role for PACAP

We are interested to have Honours, Masters and PhD students join our team to investigate the role of PACAP and it's receptors in several models of sleep apnoea. We have exciting evi more...

Supervisor(s): Farnham, Melissa (Dr)