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REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Investigation of the role of microRNAs in cell differentiation

Investigating the role of microRNAs in the regulation of stem cell multipotency and differentiation. more...

Supervisor(s): Rasko, John (Professor)

Molecular investigations of receptors involved in neurological disorders

The Laboratory of Molecular Neuroscience investigates molecular regulation and drug interactions that occur in receptors associated with neurological diseases. more...

Supervisor(s): Holsinger, Damian (Dr)

Phosphate homeostasis and fungal virulence

Inorganic phosphate (Pi) is an important macronutrient for all living organisms including yeast, and is essential for ATP, phospholipid and protein synthesis, metabolism and signall more...

Supervisor(s): Djordjevic, Julianne (Dr), Sorrell, Tania (Professor)

A weighty problem- how the protein TPD52 regulates cellular lipid storage

This project seeks to better understand why some cancer cells contain high levels of stored lipid, and whether this property can be targeted for cancer therapy. more...

Supervisor(s): Byrne, Jennifer (Professor), Chen, Yuyan (Dr)

Phosphoproteomics in early T-cell signalling

Using phospho-proteomics to understand T-cell signalling/signal transduction. more...

Supervisor(s): Manolios, Nicholas (Professor)

THE USE OF MARIJUANA AND/OR ENDOCANNABINOID OILS FOR THE TREATMENT OF OSTEOARTHRITIS (OA)

Pre-clinical studies for the effects of CBD and analogues for the treatment of osteoarthritis more...

Supervisor(s): Manolios, Nicholas (Professor), Arnold, Jonathon (Associate Professor)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Dysferlin and defective membrane repair in muscular dystrophy

We are studying a form of muscular dystrophy caused by deficiency of the protein dysferlin. Dysferlin patients have a primary defect in skeletal muscle membrane repair, and are unab more...

Supervisor(s): Cooper, Sandra (Dr)

Advanced Instrumentation and Computational Methods for in vivo Molecular Imaging

There are opportunities for physics and engineering graduates to undertake research leading to a PhD with the medical imaging physics group at the University of Sydney node of the N more...

Supervisor(s): Meikle, Steven (Professor)