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RNA-based biomarkers to understand and predict disease progression

RNA-based biomarkers are becoming increasingly important due to their stability and sensitivity of detection. This project will use in vitro, in vivo and clinical sample analysis b more...

Supervisor(s): Hardikar, Anandwardhan (Associate Professor)

Dysregulation of the inflammatory response in diabetes: Its role in poor wound healing

Diabetes is known to alter inflammatroy response but how this contributes to poor wound healing and other complications of diabetes is not known and will be investigated in this wor more...

Supervisor(s): McLennan, Susan (Dr), Shackel, Nicholas (Dr)

The Role of Extracellular Matrix Metalloprotease Inducer (EMMPRIN) in Liver Disease

The role of the hepatocyte in progressive liver injury. more...

Supervisor(s): Shackel, Nicholas (Dr)

Molecular studies of thyroid cancer and cutaneous squamous cell carcinoma

Identification of novel genes and miRNAs as predictors of thyroid cancer progression. more...

Supervisor(s): McLennan, Susan (Dr)

MicroRNAs as Regulators of Cellular Programs

This project involves modeling the role of transcription factors and miRNAs in the control of systems implicated in maintaining and regaining optimal health. more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)

Inhertied and acquired platelet function defects

Bleeding defects in Australian patients and families will be characterised using genomic and proteomic analysis more...

Supervisor(s): Ward, Chris (Professor)

Understanding how Flaviviruses interact with the host immune system to cause disease

This laboratory is investigating the interaction of neurotropic Flaviviruses with the vertebrate host immune system to discover how it causes immune-mediated disease (immunopatholog more...

Supervisor(s): King, Nicholas (Professor)

Investigating the links between telomerase and the DNA damage response in cancer cells

The ribonucleoprotein enzyme telomerase counteracts telomere shortening in a majority of cancers, allowing for unlimited cell division. Most normal cells do not express telomerase, more...

Supervisor(s): Bryan, Tracy (Professor)

An investigation into the mechanisms of immune evasion in metastatic melanoma patients treated with molecular or immune checkpoint inhibitors.

The aim of this project is to characterise the immune reaction and prevalence of immune inhibitory mechanisms present in metastatic melanoma patient tumours whilst on immune checkpo more...

Supervisor(s): Scolyer, Richard (Professor), Long, Georgina (Professor)