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Understanding how Flaviviruses interact with the host immune system to cause disease

This laboratory is investigating the interaction of neurotropic Flaviviruses with the vertebrate host immune system to discover how it causes immune-mediated disease (immunopatholog more...

Supervisor(s): King, Nicholas (Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Novel inhalation formulation to improve quality of life of cystic fibrosis sufferers

Respiratory infection is the number one cause of death world-wide with limited therapies other than tablet or intravenous injection. This multi-faceted PhD project will focus on dev more...

Supervisor(s): Traini, Daniela (Professor)

Investigation of the role of microRNAs in cell differentiation

Investigating the role of microRNAs in the regulation of stem cell multipotency and differentiation. more...

Supervisor(s): Rasko, John (Professor)

Molecular investigations of receptors involved in neurological disorders

The Laboratory of Molecular Neuroscience investigates molecular regulation and drug interactions that occur in receptors associated with neurological diseases. more...

Supervisor(s): Holsinger, Damian (Dr)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Determining the functional significance of non-coding DNA variants in genes for complex traits involving gene-environmental interactions

To identify non-protein coding DNA changes in genes that interact with the environment using 2 models – sporadic amyotrophic lateral sclerosis for the vulnerability to environ more...

Supervisor(s): Yu, Bing (Associate Professor)

Genetic control of resistance and susceptibility to tuberculosis

Both environmental and genetic factors influence susceptibility to tuberculosis; this project will identify and investigate polymorphisms in genes that may increase susceptibility t more...

Supervisor(s): Saunders, Bernadette (Dr)

Unravelling mechanisms determining the balance between tolerance and immunity in the liver

Role of primary T cell activation in the liver in CD8 T cell tolerance more...

Supervisor(s): Bertolino, Patrick (Dr)

Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)