About Associate Professor Tracy Bryan

Dr Bryan's research focusses on the role of telomeres in the growth of cancer cells, and in particular on dissecting biochemical mechanisms of telomerase action.

Dr Bryan discovered a new mechanism for cell immortalization called ALT, and has since established her own laboratory to continue studies into the role of telomeres in human tumours.

Tracy Bryan obtained her Bachelor of Science degree from Macquarie University, and then spent two years working on the genetics of colon cancer at the Johns Hopkins Hospital in Baltimore, USA, before returning to Australia to take up a PhD studentship in 1993. During her PhD studies with Roger Reddel at the CMRI she discovered a new mechanism for maintaining the ends of chromosomes, called telomeres, in human tumours. This mechanism was called ALT. Dr. Bryan spent four years conducting postdoctoral research at the University of Colorado, USA, where she carried out biochemical studies on the enzyme telomerase, which is responsible for adding DNA to telomeres. She returned to Australia to establish her own research programme at the CMRI in 2001. Her research continues to focus on the role of telomeres in the growth of cancer cells, and in particular on dissecting biochemical mechanisms of telomerase action. The opportunity to establish her own laboratory group at the CMRI played a major part in Dr Bryan’s decision to return to Australia, where the CMRI continues to provide an intellectually stimulating and supportive place in which to do research.

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Selected publications

For a comprehensive list of Dr Bryan's publicatons, please visit her Sydney Medical School profile page.