About Dr Mark Graham

Dr Mark Graham works at the interface of chemistry and biology, since many of the greatest breakthroughs in biology have been driven by improved molecular analysis. His work is guided by the principal that disease prevention will require a greater understanding of molecular mechanisms and cellular signalling pathways.

Dr Graham’s main interest is in determining the function of proteins in important biological processes. His efforts are focused on the phospho-regulated proteins involved in neurotransmission, particularly in the process of synaptic vesicle recycling and synaptic plasticity.

Dr Graham started his science career in chemistry but has now spent over ten years as a biochemist. He has over thirty research articles, many of which were published in high impact journals, including Science, Nature Cell Biology and Nature Neuroscience. He has a national reputation as a phosphoproteomics expert with a strong emphasis on delivering outcomes to biological and medical research. He was the recipient of the 2008 ASBMB Applied Biosystems Award for his contribution to biochemistry. His main interest is in neuroscience, where he has made an impact mapping the signalling which occurs at synapses during neurotransmission. This information is fundamental to understanding how molecular machines are used in the brain to adapt to stimuli. He also continues to make contributions to cancer research related to signalling and protein interactions.

Selected publications

For a comprehensive list of Dr Graham's publicatons, please visit his Sydney Medical School profile page.