Research_

Healthy volunteers for new generation nebuliser research

Take part in a research study which aims to investigate pulmonary deposition of aerosols, generated by a new generation nebuliser, Surface Acoustic Wave (SAW) nebuliser, in lungs of healthy people with no lung disease.

The results of this study will give us insight into whether the SAW nebuliser requires more optimisation or if it is ready for further in vivo study with therapeutic agents.

The study is being conducted at St George Hospital (February to March 2019) by researchers from St George Hospital, School of Pharmacy at the University of Sydney and School of Engineering at the RMIT University.

If you agree to participate in this study, you will be asked to sign the Participant Consent Form. You will then be asked to attend the Department of Nuclear Medicine at St George Hospital on a maximum of 2 occasions. 

You will be reimbursed for your time and reasonable travel expenses to the amount of $35 per visit.

Ethics approval: HREC/18/RPAH/390 

Eligibility

You may be eligible to participate in this study if you:

  • Are male aged 18 to 60 yrs
  • Are female aged 40 to 60 yrs
  • Have a Body Mass Index (BMI) < 30 kg/m2.
  • Have never been a regular smoker of tobacco
  • Have no evidence of significant cardiovascular, haematological, hepatic, pulmonary, renal, neurologic, or psychiatric disease.
  • Have no history of sleep disordered breathing.
  • Have no history or asthma.
  • Have no upper or lower respiratory tract infection within the previous 4 weeks.
  • Have no known or suspected allergy or adverse responses to 99mTc-DTPA or saline.
  • Are not pregnant or breastfeeding.

How to participate

If you are interested in the study and would like to have more information, please contact Philip Kwok (02 8627 6456 or 0413477911 or philip.kwok@sydney.edu.au) or Patricia Tang (02 9351 2516 or 0422775885 or patricia.tang@sydney.edu.au).