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Volunteer in a trial to determine if prescribed fluid intake slows the growth of kidney cysts

To participate patients must be diagnosed with polycystic kidney disease

Randomised controlled trial to determine the efficacy and safety of prescribed water intake to prevent kidney failure due to autosomal dominant polycystic kidney disease (PREVENT-ADPKD).

We are currently recruiting people with Autosomal Dominant Polycystic Kidney Disease (ADPKD) for the PREVENT-ADPKD trial. The aim of the trial is to determine if prescribed fluid intake slows the growth of kidney cysts in ADPKD.

In summary:

  • It is a 3 year study with 9 study visits
  • There will be 3 renal MRIs – one at the start, mid-way and end of the 3 years.
  • You will be required to complete 24-hour urine collections and blood tests at Douglass Hanly Moir at certain time points in the study.
  • The treatment of the study is prescribed water intake over 3 years.

We very much appreciate your help and support with this study. Your participation will be invaluable in helping find a treatment for Polycystic Kidney Disease. Please do not hesitate to contact the trial coordinator should you have any questions.
This study has received ethics approval from the Western Sydney Local Health District Human Research Ethics Committee (Reference No. 4129: AU RED HREC/14/WMEAD/414)


To be eligible to participate patients must meet the following criteria:

  • Diagnosed with polycystic kidney disease.
  • Aged 18-65 years old.
  • eGFR ≥ 30 mL/min/1.73 m2.
  • Have not received dialysis or a kidney transplant.

How to participate

If you are interested in assisting with this important and exciting area of research, please contact the study facilitator:

Prevent ADPKD