8:50 | Opening of Symposium: Prof. Trevor Hambley (Dean of Science) |
9:00 | Plenary presentation: Prof. Annette Beck-Sickinger (Universität Leipzig) Semi-synthesis of proteins to expand biological function |
9:40 | Session 1 (studying macromolecules). Session chair: A/Prof. Richard Payne |
Joel Mackay - Integrative structural analysis of a 1-MDa chromatin remodeling complex | |
Rob Thompson - Probing the effects of post-translational modifications on the activity of tick-derived anticoagulants | |
Sandro Ataide - The Signal Recognition Particle RNA and its multi functions | |
Jacqui Matthews - Protein Engineering and Transcriptional Regulation | |
11:00 | Morning tea |
11:30 | Session 2 (enabling technologies on campus). Session chair: Prof. Kate Jolliffe |
Ann Kwan - SMB NMR Facility and chemical biology | |
Adrian Smith - The Advanced Cytometry Facility - enabling technologies for single cell analysis | |
Pam Young - Cellular Imaging Facility in the Charles Perkins Centre: A Node of Sydney Microscopy and Microanalysis | |
Ben Crossett - What is the MSCF? | |
12:00 | 3-Minute poster presentations. Session chair: Prof. Kate Jolliffe |
12:50 | Lunch and poster session |
14:00 | Session 3 (targeting and imaging). Session chair: A/Prof. Renae Ryan |
Margie Sunde - Using amyloid to your advantage - functional fibrils from fungal hydrophobin proteins | |
Peter Rutledge - Visualising ion flux with small molecule probes, and nanoparticles | |
Andrew Katsifis - TBD | |
Phil Robinson - TBD | |
Liz New - Molecular imaging tools for intracellular redox state and biological metal ions | |
15:40 | Afternoon tea and poster session |
16:00 | Session 4 (developing active small molecules). Session chair: Dr Benjamin Parker |
Mary Collins - Multiple binding interfaces on nACh receptors allude to stoichiometric dependent actions of antagonists | |
Rachel Codd - New siderophore scaffolds from precursor-directed biosynthesis | |
Paul Witting - Pre-treatment with the synthetic antioxidant T-butyl bisphenol protects cerebral tissues from experimental ischemia reperfusion injury | |
Lenka Munoz - Development of allosteric MK2 inhibitors with blood-brain barrier permeability | |
17:20 | Plenary presentation: Dr James Crawford (Genentech) Potent and Selective Pyridone BTK Inhibitors With Activity Against Mutant Forms of BTK |
18:00 | Closing remarks Drinks reception (Law Foyer) |